COPD[業績]

• 2019年

  1. Tanabe N, Sato S, Muro S, Shima H, Oguma T, Tanimura K, Sato A, Hirai T. Regional lung deflation with increased airway volume underlies the functional response to bronchodilators in chronic obstructive pulmonary disease. Physiol Rep. 2019 Dec 26;7(24):263–9.
  2. McDonough JE, Ahangari F, Li Q, Jain S, Verleden SE, Herazo-Maya J, Vukmirovic M, DeIuliis G, Tzouvelekis A, Tanabe N, Chu F, Yan X, Verschakelen J, Homer RJ, Manatakis DV, Zhang J, Ding J, Maes K, De Sadeleer L, Vos R, Neyrinck A, Benos PV, Bar-Joseph Z, Tantin D, Hogg JC, Vanaudenaerde BM, Wuyts WA, Kaminski N. Transcriptional regulatory model of fibrosis progression in the human lung. JCI Insight. 2019 Nov 14;4(22):67.
  3. Kirby M, Tanabe N, Vasilescu DM, Cooper JD, McDonough JE, Verleden SE, Vanaudenaerde BM, Sin DD, Tan WC, Coxson HO, Hogg JC. Computed Tomography Total Airway Count is Associated with Number of Micro-CT Terminal Bronchioles. Am J Respir Crit Care Med. 2019 Nov 7;:rccm.201910–1948LE.
  4. Tanabe N, Shima H, Sato S, Oguma T, Kubo T, Kozawa S, Koizumi K, Sato A, Togashi K, Hirai T. Direct evaluation of peripheral airways using ultra-high-resolution CT in chronic obstructive pulmonary disease. Eur J Radiol. 2019 Sep 20;120:108687.
  5. Mochizuki F, Iijima H, Watanabe A, Tanabe N, Sato S, Shiigai M, Fujiwara K, Shimada T, Ishikawa H, Kanazawa J, Yatagai Y, Masuko H, Sakamoto T, Muro S, Hizawa N. The Concavity of the Maximal Expiratory Flow-Volume Curve Reflects the Extent of Emphysema in Obstructive Lung Diseases. Sci Rep. 2019 Sep 11;9(1):13159.
  6. Vasilescu DM, Martinez FJ, Marchetti N, Galbán CJ, Hatt C, Meldrum CA, Dass C, Tanabe N, Reddy RM, Lagstein A, Ross BD, Labaki WW, Murray S, Meng X, Curtis JL, Hackett TL, Kazerooni EA, Criner GJ, Hogg JC, Han MK. Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2019 Sep 1;200(5):575–81.
  7. Oshima A, Nishimura A, Chen-Yoshikawa TF, Harashima S-I, Komatsu T, Handa T, Aoyama A, Takahashi K, Ikeda M, Oshima Y, Ikezoe K, Sato S, Isomi M, Shide K, Date H, Inagaki N. Nutrition-related factors associated with waiting list mortality in patients with interstitial lung disease: A retrospective cohort study. Clin Transplant. 2019 Jun;33(6):e13566.
  8. Tanabe N, Sato S, Oguma T, Shima H, Sato A, Muro S, Hirai T. Associations of airway tree to lung volume ratio on computed tomography with lung function and symptoms in chronic obstructive pulmonary disease. Respir Res. BioMed Central; 2019 Apr 18;20(1):77.
  9. Uemasu K, Sato S, Muro S, Sato A, Tanabe N, Hasegawa K, Hamakawa Y, Mizutani T, Fuseya Y, Tanimura K, Takahashi T, Hirai T. Annual decline in arterial blood oxygen predicts development of chronic respiratory failure in COPD with mild hypoxaemia: A 6-year follow-up study. Respirology. 2019 Mar;24(3):262–9.
  10. Fuseya Y, Muro S, Sato S, Sato A, Tanimura K, Hasegawa K, Uemasu K, Hamakawa Y, Takahashi Y, Nakayama T, Sakai N, Fukui M, Kita H, Mio T, Mishima M, Hirai T. Perspectives on End-of-Life Treatment among Patients with COPD: A Multicenter, Cross-sectional Study in Japan. COPD. 2019 Feb;16(1):75–81. 
Mondoñedo JR, Sato S, Oguma T, Muro S, Sonnenberg AH, Zeldich D, Parameswaran H, Hirai T, Suki B. CT Imaging-Based Low-Attenuation Super Clusters in Three Dimensions and the Progression of Emphysema. Chest. 2019 Jan;155(1):79–87.

  2018年

  1. Fuseya Y, Muro S, Sato S, Tanabe N, Sato A, Tanimura K, Hasegawa K, Uemasu K, Kubo T, Kido A, Fujimoto K, Fushimi Y, Kusahara H, Sakashita N, Ohno Y, Togashi K, Mishima M, Hirai T. Complementary regional heterogeneity information from COPD patients obtained using oxygen-enhanced MRI and chest CT. Vij N, ed. PLoS ONE. 2018;13(8):e0203273. doi:10.1371/journal.pone.0203273.
  2. Yoshimura K, Sato S, Muro S, Yamada M, Hasegawa K, Kiyokawa H, Mishima M, Aoyama T. Interdependence of physical inactivity, loss of muscle mass and low dietary intake: Extrapulmonary manifestations in older chronic obstructive pulmonary disease patients. Geriatr Gerontol Int. 2018;18(1):88-94. doi:10.1111/ggi.13146.
  3. Nagata K, Kikuchi T, Horie T, Shiraki A, Kitajima T, Kadowaki T, Tokioka F, Chohnabayashi N, Watanabe A, Sato S, Tomii K. Domiciliary High-Flow Nasal Cannula Oxygen Therapy for Patients with Stable Hypercapnic Chronic Obstructive Pulmonary Disease. A Multicenter Randomized Crossover Trial. Ann Am Thorac Soc. 2018;15(4):432-439. doi:10.1513/AnnalsATS.201706-425OC.
  4. Hasegawa K, Sato S, Tanimura K, Fuseya Y, Uemasu K, Hamakawa Y, Sato A, Mishima M, Muro S, Hirai T. Gastroesophageal reflux symptoms and nasal symptoms affect the severity of bronchitis symptoms in patients with chronic obstructive pulmonary disease. Respir Investig. 2018;56(3):230-237. doi:10.1016/j.resinv.2018.01.001.
  5. Ito J, Nagata K, Sato S, Shiraki A, Nishimura N, Izumi S, Tachikawa R, Morimoto T, Tomii K. The clinical practice of high-flow nasal cannula oxygen therapy in adults: A Japanese cross-sectional multicenter survey. Respir Investig. 2018;56(3):249-257. doi:10.1016/j.resinv.2018.02.002.
  6. Shioya T, Sato S, Iwakura M, Takahashi H, Terui Y, Uemura S, Satake M. Improvement of physical activity in chronic obstructive pulmonary disease by pulmonary rehabilitation and pharmacological treatment. Respir Investig. 2018;56(4):292-306. doi:10.1016/j.resinv.2018.05.002.
  7. Tanabe N, Muro S, Sato S, Oguma T, Sato A, Hirai T. Fractal analysis of low attenuation clusters on computed tomography in chronic obstructive pulmonary disease. BMC Pulm Med. 2018;18(1):144. doi:10.1186/s12890-018-0714-5.
  8. Uemasu K, Sato S, Muro S, Sato A, Tanabe N, Hasegawa K, Hamakawa Y, Mizutani T, Fuseya Y, Tanimura K, Takahashi T, Hirai T. Annual decline in arterial blood oxygen predicts development of chronic respiratory failure in COPD with mild hypoxaemia: A 6-year follow-up study. Respirology. 2018;6:199. doi:10.1111/resp.13402.
  9. Suzuki M, Muro S, Fukui M, Ishizaki N, Sato S, Shiota T, Endo K, Suzuki T, Mitsuma T, Mishima M, Hirai T. Effects of acupuncture on nutritional state of patients with stable chronic obstructive pulmonary disease (COPD): re-analysis of COPD acupuncture trial, a randomized controlled trial. BMC Complement Altern Med. 2018;18(1):287. doi:10.1186/s12906-018-2341-3.
  10. Tanabe N, Oguma T, Sato S, Kubo T, Kozawa S, Shima H, Koizumi K, Sato A, Muro S, Togashi K, Hirai T. Quantitative measurement of airway dimensions using ultra-high resolution computed tomography. Respir Investig. 2018;56(6):489-496. doi:10.1016/j.resinv.2018.07.008.
  11. Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO, CanCOLD Collaborative Research Group, Canadian Respiratory Research Network, CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network. Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study. Am J Respir Crit Care Med. 2018;197(1):56-65. doi:10.1164/rccm.201704-0692OC.
  12. Tanabe N, Vasilescu DM, Kirby M, Coxson HO, Verleden SE, Vanaudenaerde BM, Kinose D, Nakano Y, Paré PD, Hogg JC. Analysis of airway pathology in COPD using a combination of computed tomography, micro-computed tomography and histology. Eur Respir J. 2018;51(2):1701245. doi:10.1183/13993003.01245-2017.
  13. McDonough JE, Martens DS, Tanabe N, Ahangari F, Verleden SE, Maes K, Verleden GM, Kaminski N, Hogg JC, Nawrot TS, Wuyts WA, Vanaudenaerde BM. A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis. Respir Res. 2018;19(1):132. doi:10.1186/s12931-018-0838-4.
  14. Mondoñedo JR, Sato S, Oguma T, Muro S, Sonnenberg AH, Zeldich D, Parameswaran H, Hirai T, Suki B. CT-Based Low-Attenuation Super Clusters in 3D and the Progression of Emphysema. Chest. October 2018. doi:10.1016/j.chest.2018.09.014.

  2017年

  1. Kamada T, Ito I, Kanemitsu Y, Sato S, Matsumoto H, Niimi A, Mishima M. Three-dimensional imaging forced oscillation technique to assess position-dependent airway obstruction in relapsing polychondritis: A case report. Respir Investig. 2017 Jan;55(1):69–73.
  2. Vasilescu DM, Phillion AB, Tanabe N, Kinose D, Paige DF, Kantrowitz JJ, Liu G, Liu H, Fishbane N, Verleden SE, Vanaudenaerde BM, Lenburg M, Stevenson CS, Spira A, Cooper JD, Hackett T-L, Hogg JC. Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue. Journal of applied physiology. 2017 Jan 1;122(1):161–9.
  3. Tanabe N, Vasilescu DM, McDonough JE, Kinose D, Suzuki M, Cooper JD, Paré PD, Hogg JC. Micro-Computed Tomography Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema. Am J Respir Crit Care Med. 2017 Mar 1;195(5):630–8.
  4. Matsumoto T, Tabara Y, Murase K, Takahashi Y, Setoh K, Kawaguchi T, Muro S, Kadotani H, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda F, Chin K. Combined association of clinical and lifestyle factors with non-restorative sleep: The Nagahama Study. PLoS ONE. 2017;12(3):e0171849.
  5. Sokai A, Tanizawa K, Handa T, Kubo T, Hashimoto S, Ikezoe K, Nakatsuka Y, Aihara K, Taguchi Y, Muro S, Oga T, Nagai S, Izumi T, Hirai T, Chin K, Mishima M. Asymmetry in acute exacerbation of idiopathic pulmonary fibrosis. ERJ Open Res. European Respiratory Society; 2017 Apr;3(2):00036–2016.
  6. Matsumoto H, Izuhara Y, Niimi A, Tabara Y, Nagasaki T, Kanemitsu Y, Murase K, Oguma T, Ito I, Muro S, Sekine A, Matsuda F, Kosugi S, Nakayama T, Chin K, Mishima M, Nagahama Study Collaboration Group. Risks and Cough-Aggravating Factors in Prolonged Cough. Epidemiological Observations from the Nagahama Cohort Study. Ann Am Thorac Soc. 2017 May;14(5):698–705.
  7. Nagami S, Oku Y, Yagi N, Sato S, Uozumi R, Morita S, Yamagata Y, Kayashita J, Tanimura K, Sato A, Takahashi R, Muro S. Breathing-swallowing discoordination is associated with frequent exacerbations of COPD. BMJ Open Respir Res. 2017 Jun 5;4(1):e000202–10.
  8. Ikezoe K, Handa T, Tanizawa K, Yokoi H, Kubo T, Aihara K, Sokai A, Nakatsuka Y, Hashimoto S, Uemasu K, Sato S, Muro S, Nagai S, Yanagita M, Chin K, Hirai T, Taguchi Y, Mishima M. Chronic Kidney Disease Predicts Survival in Patients with Idiopathic Pulmonary Fibrosis. Respiration. 2017;94(4):346–54.
  9. Yoshimura K, Sato S, Muro S, Yamada M, Hasegawa K, Kiyokawa H, Mishima M, Aoyama T. Interdependence of physical inactivity, loss of muscle mass and low dietary intake: Extrapulmonary manifestations in older chronic obstructive pulmonary disease patients. Geriatr Gerontol Int. 2017 Aug 4;187(1):347.
  10. Hasegawa K, Sato A, Tanimura K, Uemasu K, Hamakawa Y, Fuseya Y, Sato S, Muro S, Hirai T. Fraction of MHCII and EpCAM expression characterizes distal lung epithelial cells for alveolar type 2 cell isolation. Respir Res. BioMed Central; 2017 Aug 7;18(1):150.
  11. Yamamoto Y, Gotoh S, Korogi Y, Seki M, Konishi S, Ikeo S, Sone N, Nagasaki T, Matsumoto H, Muro S, Ito I, Hirai T, Kohno T, Suzuki Y, Mishima M. Long-term expansion of alveolar stem cells derived from human iPS cells in organoids. Nat Methods. Nature Publishing Group; 2017 Nov;14(11):1097–106.
  12. Nagata K, Kikuchi T, Horie T, Shiraki A, Kitajima T, Kadowaki T, Tokioka F, Chohnabayashi N, Watanabe A, Sato S, Tomii K. Domiciliary High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic COPD Patients: A Multicenter, Randomized Crossover Trial. Ann Am Thorac Soc. 2017 Dec 28;:AnnalsATS.201706–425OC.

  2016年

  1. Shikuma K, Menju T, Chen F, Kubo T, Muro S, Sumiyoshi S, Ohata K, Sowa T,　Nakanishi T, Cho H, Neri S, Aoyama A, Sato T, Sonobe M, Date H. Is volumetric　3-dimensional computed tomography useful to predict histological tumour　invasiveness? Analysis of 211 lesions of cT1N0M0 lung adenocarcinoma. Interact　Cardiovasc Thorac Surg. 2016 Jun;22(6):831-8.
  2. Tsao PN, Matsuoka C, Wei SC, Sato A, Sato S, Hasegawa K, Chen HK, Ling TY, Mori M, Cardoso WV, Morimoto M.　Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8242-7. doi: 10.1073/pnas.1511236113.
  3. Hamada S, Sato A, Hara-Chikuma M, Satooka H, Hasegawa K, Tanimura K, Tanizawa K, Inouchi M, Handa T, Oga T, Muro S, Mishima M, Chin K.　 Role of mitochondrial hydrogen peroxide induced by intermittent hypoxia in airway epithelial wound repair in vitro.　Exp Cell Res. 2016 May 15;344(1):143-51. doi: 10.1016/j.yexcr.2016.04.006.
  4. Muro S, Tabara Y, Matsumoto H, Setoh K, Kawaguchi T, Takahashi M, Ito I, Ito　Y, Murase K, Terao C, Kosugi S, Yamada R, Sekine A, Nakayama T, Chin K, Mishima　M, Matsuda F; Nagahama Study Group.. Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary　Disease in A General Japanese Population: The Nagahama Study. Medicine　(Baltimore). 2016 Apr;95(15):e3371.
  5. Yi E, Sato S, Takahashi A, et al. Mechanical Forces Accelerate Collagen Digestion by Bacterial Collagenase in Lung Tissue Strips.Frontiers in Physiology. 2016;7:287. doi:10.3389/fphys.2016.00287.

  2015年

  1. Tanimura K, Sato S, Fuseya Y, Hasegawa K, Uemasu K, Sato A, Oguma T, Hirai T,
     Mishima M, Muro S. Quantitative Assessment of Erector Spinae Muscles in Patients
     with Chronic Obstructive Pulmonary Disease. Novel Chest Computed
     Tomography-derived Index for Prognosis. Ann Am Thorac Soc. 2016 Mar;13(3):334-41.
     doi: 10.1513/AnnalsATS.201507-446OC. PubMed PMID: 26700501.
  2. Konishi S, Gotoh S, Tateishi K, Yamamoto Y, Korogi Y, Nagasaki T, Matsumoto H,
     Muro S, Hirai T, Ito I, Tsukita S, Mishima M. Directed Induction of Functional
     Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human
     Pluripotent Stem Cells. Stem Cell Reports. 2016 Jan 12;6(1):18-25. doi:
     10.1016/j.stemcr.2015.11.010. Epub 2015 Dec 24. PubMed PMID: 26724905; PubMed
     Central PMCID: PMC4720023.
  3. Kinose D, Ogawa E, Kudo M, Marumo S, Kiyokawa H, Hoshino Y, Hirai T, Chin K,
     Muro S, Mishima M. Association of COPD exacerbation frequency with gene
     expression of pattern recognition receptors in inflammatory cells in induced
     sputum. Clin Respir J. 2016 Jan;10(1):11-21. doi: 10.1111/crj.12171. Epub 2014
     Aug 13. PubMed PMID: 24902764.
  4. Sokai A, Handa T, Tanizawa K, Oga T, Uno K, Tsuruyama T, Kubo T, Ikezoe K,
     Nakatsuka Y, Tanimura K, Muro S, Hirai T, Nagai S, Chin K, Mishima M. Matrix
     metalloproteinase-10: a novel biomarker for idiopathic pulmonary fibrosis. Respir
     Res. 2015 Sep 29;16:120. doi: 10.1186/s12931-015-0280-9. PubMed PMID: 26415518;
     PubMed Central PMCID: PMC4587921.
  5. Ikezoe K, Handa T, Tanizawa K, Kubo T, Oguma T, Hamada S, Watanabe K, Aihara
     K, Sokai A, Nakatsuka Y, Muro S, Nagai S, Uno K, Chin K, Fukui M, Hirai T,
     Mishima M. Bone mineral density in patients with idiopathic pulmonary fibrosis.
     Respir Med. 2015 Sep;109(9):1181-7. doi: 10.1016/j.rmed.2015.06.014. Epub 2015
     Jul 6. PubMed PMID: 26174191.
  6. Oguma T, Hirai T, Fukui M, Tanabe N, Marumo S, Nakamura H, Ito H, Sato S,
     Niimi A, Ito I, Matsumoto H, Muro S, Mishima M. Longitudinal shape irregularity
     of airway lumen assessed by CT in patients with bronchial asthma and COPD.
     Thorax. 2015 Aug;70(8):719-24. doi: 10.1136/thoraxjnl-2014-206651. Epub 2015 May
     29. PubMed PMID: 26024690.
  7. Setoh K, Terao C, Muro S, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T,
     Kosugi S, Sekine A, Yamada R, Mishima M, Matsuda F. Three missense variants of
     metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels.
     Nat Commun. 2015 Jul 15;6:7754. doi: 10.1038/ncomms8754. PubMed PMID: 26174136;
     PubMed Central PMCID: PMC4518310.
  8. Hasegawa K, Sato S, Tanimura K, Fuseya Y, Uemasu K, Sato A, Hirai T, Mishima
     M, Muro S. Emphysema and airway disease affect within-breath changes in
     respiratory resistance in COPD patients. Respirology. 2015 Jul;20(5):775-81. doi:
     10.1111/resp.12535. Epub 2015 Mar 30. PubMed PMID: 25824559.

  2014年

  1. Tabara Y, Muro S, Takahashi Y, Setoh K, Kawaguchi T, Terao C, Kosugi S, Sekine
     A, Yamada R, Nakayama T, Mishima M, Matsuda F; Nagahama Study Group. Airflow
     limitation in smokers is associated with arterial stiffness: the Nagahama Study.
     Atherosclerosis. 2014 Jan;232(1):59-64.
  2. Marumo S, Hoshino Y, Kiyokawa H, Tanabe N, Sato A, Ogawa E, Muro S, Hirai T,
     Mishima M. p38 mitogen-activated protein kinase determines the susceptibility to
     cigarette smoke-induced emphysema in mice. BMC Pulm Med. 2014 May 7;14:79. doi:
     10.1186/1471-2466-14-79.
  3. Kinose D, Ogawa E, Kudo M, Marumo S, Kiyokawa H, Hoshino Y, Hirai T, Chin K,
     Muro S, Mishima M. Association of COPD exacerbation frequency with gene
     expression of pattern recognition receptors in inflammatory cells in induced
     sputum. Clin Respir J. 2014 Jun 5.
  4. Tanimura K, Hirai T, Sato S, Hasegawa K, Muro S, Kurosawa H, Mishima M.
     Comparison of two devices for respiratory impedance measurement using a forced
     oscillation technique: basic study using phantom models. J Physiol Sci. 2014
     Sep;64(5):377-82.
  5. 室　繁郎
     【COPD治療の新時代　21世紀の「社会的」生活習慣病】 COPDの早期診断,治療の枠組み,急性増悪の対応　新薬乱立の前に知っておくべきこと
     内科(0022-1961)113巻2号 Page217-225(2014.02)
  6. 室　繁郎
     【喘息・COPD患者への吸入指導】 COPDの診断と治療　ガイドラインをふまえて
     薬事(0016-5980)56巻3号 Page327-332(2014.03)
  7. 佐藤 篤靖, 室 繁郎
     【COPDを改めて問う】 COPDにおける併存症　気流閉塞、肺気腫いずれに関与しているのか
     THE LUNG-perspectives(0919-5742)22巻2号 Page171-174(2014.05)
  8. 室　繁郎
     【COPDの最新情報】 (Topics 5)併存症・合併症のインパクトとその対策
     日本呼吸器学会誌(2186-5876)3巻3号 Page344-351(2014.05)
  9. 佐藤 晋, 室 繁郎
     【疾患と運動時低酸素血症】 COPDと運動時低酸素血症
     呼吸と循環(0452-3458)62巻6号 Page545-551(2014.06)
  10. 佐藤 晋, 室 繁郎, 三嶋 理晃
      【高齢者の呼吸器疾患-若年・高齢者発症との違い-】 COPD　若年発症COPDと高齢者COPDについて
      日本胸部臨床(0385-3667)73巻8号 Page876-885(2014.08)
  11. 佐藤 晋, 室 繁郎
      【全身成人病としてのCOPD】 COPDの呼吸機能
      成人病と生活習慣病(1347-0418)44巻9号 Page1013-1018(2014.09)
  12. 室　繁郎
      呼吸器疾患診療を支える臨床検査 COPD診療における呼吸機能とCT画像の役割
      臨床病理(0047-1860)62巻12号 Page1212-1217(2014.12)

  2013年

  1. Tabara Y, Takahashi Y, Setoh K, Muro S, Kawaguchi T, Terao C, Kosugi S, Sekine A, Yamada R, Mishima M, Nakayama T, Matsuda F; on behalf of the Nagahama Study Group. Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: The Nagahama Study. Int J Cardiol. 2013 Apr 8. doi:pii: S0167-5273(13)00447-6. 10.1016/j.ijcard.2013.03.028. [Epub ahead of print]
  2. Oguma T, Hirai T, Niimi A, Matsumoto H, Muro S, Shigematsu M, Nishimura T, Kubo Y, Mishima M. Limitations of airway dimension measurement on images obtained using multi-detector row computed tomography. PLoS One. 2013 Oct 8;8(10):e76381. doi: 10.1371/journal.pone.0076381.
  3. Tanabe N, Hoshino Y, Marumo S, Kiyokawa H, Sato S, Kinose D, Uno K, Muro S, Hirai T, Yodoi J, Mishima M. Thioredoxin-1 Protects against Neutrophilic Inflammation and Emphysema Progression in a Mouse Model of Chronic Obstructive Pulmonary Disease Exacerbation. PLoS One. 2013 Nov 11;8(11):e79016. doi: 10.1371/journal.pone.0079016.
  4. Tabara Y, Muro S, Takahashi Y, Setoh K, Kawaguchi T, Terao C, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda F; Nagahama Study Group. Airflow limitation in smokers is associated with arterial stiffness: The Nagahama Study Atherosclerosis. 2014 Jan;232(1):59-64. doi: 10.1016/j.atherosclerosis.2013.10.020. Epub 2013 Nov 1.

  2012年

  1. Tanabe N, Muro S, Sato S, Tanaka S, Oguma T, Kiyokawa H, Takahashi T, Kinose
     D, Hoshino Y, Kubo T, Hirai T, Mishima M. Longitudinal study of spatially heterogeneous emphysema progression in current smokers with chronic obstructive
     pulmonary disease. PLoS One. 2012;7(9):e44993. doi: 10.1371/journal.pone.0044993.
     Epub 2012 Sep 18.
  2. Suzuki M, Muro S, Ando Y, Omori T, Shiota T, Endo K, Sato S, Aihara K,
     Matsumoto M, Suzuki S, Itotani R, Ishitoko M, Hara Y, Takemura M, Ueda T, Kagioka
     H, Hirabayashi M, Fukui M, Mishima M. A randomized, placebo-controlled trial of
     acupuncture in patients with chronic obstructive pulmonary disease (COPD): the
     COPD-acupuncture trial (CAT). Arch Intern Med. 2012 Jun 11;172(11):878-86.
  3. Takahashi T, Muro S, Tanabe N, Terada K, Kiyokawa H, Sato S, Hoshino Y, Ogawa
     E, Uno K, Naruishi K, Takashiba S, Mishima M. Relationship between
     periodontitis-related antibody and frequent exacerbations in chronic obstructive
     pulmonary disease. PLoS One. 2012;7(7):e40570. Epub 2012 Jul 11.
  4. Tanabe N, Muro S, Fuseya Y, Sato S, Oguma T, Kiyokawa H, Takahashi T, Kinose
     D, Hoshino Y, Kubo T, Hirai T, Mishima M. Peri-diaphragmatic lung volume assessed
     by computed tomography correlates with quality of life in patients with chronic
     obstructive pulmonary disease. Respirology. 2012 Oct;17(7):1137-43. doi:
     10.1111/j.1440-1843.2012.02221.x.
  5. Tanabe N, Muro S, Tanaka S, Sato S, Oguma T, Kiyokawa H, Takahashi T, Kinose
     D, Hoshino Y, Kubo T, Ogawa E, Hirai T, Mishima M. Emphysema distribution and
     annual changes in pulmonary function in male patients with chronic obstructive
     pulmonary disease. Respir Res. 2012 Apr 18;13:31. doi: 10.1186/1465-9921-13-31.
  6. Tanabe N, Muro S, Oguma T, Sato S, Kiyokawa H, Takahashi T, Kudo M, Kinose D,
     Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M. Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD. COPD.
     2012 Aug;9(4):401-8. Epub 2012 Apr 18.
  7. Kudo M, Ogawa E, Kinose D, Haruna A, Takahashi T, Tanabe N, Marumo S, Hoshino
     Y, Hirai T, Sakai H, Muro S, Date H, Mishima M. Oxidative stress induced
     interleukin-32 mRNA expression in human bronchial epithelial cells. Respir Res.
     2012 Mar 14;13:19.
  8. Kiyokawa H, Muro S, Oguma T, Sato S, Tanabe N, Takahashi T, Kudo M, Kinose D,
     Kondoh H, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M. Impact of COPD
     exacerbations on osteoporosis assessed by chest CT scan. COPD. 2012 Jun;9(3):235-42. Epub 2012 Feb 23.
  9. Ito Y, Hirai T, Maekawa K, Fujita K, Imai S, Tatsumi S, Handa T, Matsumoto H,
     Muro S, Niimi A, Mishima M. Predictors of 5-year mortality in pulmonary
     Mycobacterium avium-intracellulare complex disease. Int J Tuberc Lung Dis.
     2012;16(3):408-14. Epub 2012 Jan 5.

  2011年

  1. Matsumoto H, Hirata Y, Otsuka K, Iwata T, Inazumi A, Niimi A, Ito I, Ogawa E,
     Muro S, Sakai H, Chin K, Oku Y, Mishima M. Interleukin-13 enhanced Ca2+
     oscillations in airway smooth muscle cells. Cytokine. 2012 Jan;57(1):19-24. Epub
     2011 Nov 9.
  2. Hoshino Y, Muro S, Mishima M. [Novel therapeutics for COPD]. Nihon Rinsho.
     2011 Oct;69(10):1826-30. Review. Japanese.
  3. Otsuka K, Matsumoto H, Niimi A, Muro S, Ito I, Takeda T, Terada K, Yamaguchi
     M, Matsuoka H, Jinnai M, Oguma T, Nakaji H, Inoue H, Tajiri T, Iwata T, Chin K,
     Mishima M. Sputum YKL-40 levels and pathophysiology of asthma and chronic
     obstructive pulmonary disease. Respiration. 2012;83(6):507-19. doi:
     10.1159/000330840. Epub 2011 Sep 27.
  4. Kinose D, Ogawa E, Hirota T, Ito I, Kudo M, Haruna A, Marumo S, Hoshino Y,
     Muro S, Hirai T, Sakai H, Date H, Tamari M, Mishima M. A NOD2 gene polymorphism
     is associated with the prevalence and severity of chronic obstructive pulmonary
     disease in a Japanese population. Respirology. 2012 Jan;17(1):164-71. doi:
     10.1111/j.1440-1843.2011.02069.x.
  5. Tanabe N, Muro S, Hirai T, Oguma T, Terada K, Marumo S, Kinose D, Ogawa E,
     Hoshino Y, Mishima M. Impact of exacerbations on emphysema progression in chronic
     obstructive pulmonary disease. Am J Respir Crit Care Med. 2011 Jun 15;183(12):1653-9. Epub 2011 Mar 11.

  2010年

  1. Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y,
     Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M.
     Lipopolysaccharide induced connective tissue growth factor gene expression in
     human bronchial epithelial cells. Respirology. 2010 May;15(4):669-76. Epub 2010
     Mar 29.
  2. Haruna A, Muro S, Nakano Y, Ohara T, Hoshino Y, Ogawa E, Hirai T, Niimi A,
     Nishimura K, Chin K, Mishima M. CT scan findings of emphysema predict mortality
     in COPD. Chest. 2010 Sep;138(3):635-40. Epub 2010 Apr 9.
  3. Haruna A, Oga T, Muro S, Ohara T, Sato S, Marumo S, Kinose D, Terada K,
     Nishioka M, Ogawa E, Hoshino Y, Hirai T, Chin K, Mishima M. Relationship between
     peripheral airway function and patient-reported outcomes in COPD: a cross-sectional study. BMC Pulm Med. 2010 Mar 7;10:10.

  2009年

  1. IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells.Yamasaki A, Saleh A, Koussih L, Muro S, Halayko AJ, Gounni AS. PLoS One. 2010 Feb 12;5(2):e9178.
  2. Sakai H, Nakano Y, Muro S, Hirai T, Takubo Y, Oku Y, Hamakawa H, Takahashi A,
     Sato T, Chen F, Sahara H, Fujinaga T, Sato K, Sonobe M, Shoji T, Miyahara R,
     Okubo K, Bando T, Hirata T, Date H, Mishima M. Age-related changes in the trachea
     in healthy adults. Adv Exp Med Biol. 2010;662:115-20.
  3. Terada K, Muro S, Ohara T, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Chin
     K, Mishima M. Abnormal swallowing reflex and COPD exacerbations. Chest. 2010
     Feb;137(2):326-32. Epub 2009 Sep 25.
  4. Terada K, Muro S, Ohara T, Haruna A, Marumo S, Kudo M, Ogawa E, Hoshino Y,
     Hirai T, Niimi A, Mishima M. Cough-reflex sensitivity to inhaled capsaicin in
     COPD associated with increased exacerbation frequency. Respirology. 2009
     Nov;14(8):1151-5. Epub 2009 Sep 16.

  2008年

  1. Ogawa E, Nakano Y, Ohara T, Muro S, Hirai T, Sato S, Sakai H, Tsukino M,
     Kinose D, Nishioka M, Niimi A, Chin K, Paré PD, Mishima M. Body mass index in
     male patients with COPD: correlation with low attenuation areas on CT. Thorax.
     2009 Jan;64(1):20-5. Epub 2008 Oct 13.
  2. Sato, A., et al., Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice. J Pharmacol Exp Ther, 2008. 325(2): p. 380-8.
  3. Ohara, T., et al., Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography. Respirology, 2008. 13(3): p. 372-8.
  4. Terada, K., et al., Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation. Thorax, 2008.
  5. Ohara, T., et al., Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD. Chest, 2008.

  2007年以前

  1. Sato, A., et al., Morphological mechanism of the development of pulmonary emphysema in klotho mice. Proc Natl Acad Sci U S A, 2007. 104(7): p. 2361-5.
  2. Ohara, T., et al., Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD. Respirology, 2006. 11(5): p. 579-85.
  3. Ito, I., et al., Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema. Am J Respir Crit Care Med, 2005. 172(11): p. 1378-82.
  4. Ito, I., et al., Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele. Chest, 2004. 125(1): p. 63-70.
  5. Muro, S., et al., 5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin. J Allergy Clin Immunol, 2003. 112(4): p. 768-74.
  6. Muro, S., et al., Expression of IL-15 in inflammatory pulmonary diseases. J Allergy Clin Immunol, 2001. 108(6): p. 970-5.
  7. Muro, S., E.M. Minshall, and Q.A. Hamid, The pathology of chronic asthma. Clin Chest Med, 2000. 21(2): p. 225-44.
  8. Nakano, Y., et al., Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. Am J Respir Crit Care Med, 2000. 162(3 Pt 1): p. 1102-8.
  9. Muro, S., et al., Distorted trachea in patients with chronic obstructive pulmonary disease. Respiration, 2000. 67(6): p. 638-44.
  10. Nakano, Y., et al., Comparison of low attenuation areas on computed tomographic scans between inner and outer segments of the lung in patients with chronic obstructive pulmonary disease: incidence and contribution to lung function. Thorax, 1999. 54(5): p. 384-9.
  11. Mishima, M., et al., Optimized scanning conditions of high resolution CT in the follow-up of pulmonary emphysema. J Comput Assist Tomogr, 1999. 23(3): p. 380-4.
  12. Mishima, M., et al., Respiratory impedance during positive expiratory airway pressure in patients with chronic obstructive pulmonary disease. Front Med Biol Eng, 1999. 9(1): p. 63-73.
  13. Mishima, M., et al., Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A, 1999. 96(16): p. 8829-34.
  14. Takubo, Y., et al., Age-associated changes in elastin and collagen content and the proportion of types I and III collagen in the lungs of mice. Exp Gerontol, 1999. 34(3): p. 353-64.
  15. Muro, S., et al., The effect of the level of ventilatory assist on the level of respiratory drive in decerebrate cats. Respir Physiol, 1997. 109(3): p. 205-17.
  16. Mishima, M., et al., Relationship between dyspnea in daily life and psycho-physiologic state in patients with chronic obstructive pulmonary disease during long-term domiciliary oxygen therapy. Intern Med, 1996. 35(6): p. 453-8.