COPD[業績]

呼吸不全・睡眠呼吸障害　｜　間質性肺疾患　｜　COPD　｜　喘息・慢性咳嗽　｜　感染症　｜　肺がん　｜　iPS

2022年度
1. Togawa J, Matsumoto R, Usami K, Matsuhashi M, Inouchi M, Kobayashi K, Hitomi T, Nakae T, Shimotake A, Yamao Y, Kikuchi T, Yoshida K, Kunieda T, Miyamoto S, Takahashi R, Ikeda A. Enhanced phase-amplitude coupling of human electrocorticography selectively in the posterior cortical region during rapid eye movement sleep. Cereb Cortex 2022;33(2):486-496. doi: 10.1093/cercor/bhac079.
2. Sakamoto M, Matsumoto R, Shimotake A, Togawa J, Takeyama H, Kobayashi K, Leypoldt F, Wandinger KP, Kondo T, Takahashi R, Ikeda A. Diagnostic value of an algorithm for autoimmune epilepsy in a retrospective cohort. Front Neurol 2022;13:902157.
3. Nakatani M, Inouchi M, Daifu-Kobayashi M, Murai T, Togawa J, Kajikawa S, Kobayashi K, Hitomi T, Kunieda T, Hashimoto S, Inaji M, Shirozu H, Kanazawa K, Iwasaki M, Usui N, Inoue Y, Maehara T, Ikeda A. Ictal direct current shifts contribute to defining the core ictal focus in epilepsy surgery. Brain Commun 2022;4(5):fcac222. https://doi.org/10.1093/braincomms/fcac222
4. Ogawa M, Uchiumi A, Sato S, Hamakawa Y, Kobashi M, Aoyama T, Tanimukai H. Preliminary Study of Assessing Cognitive Impairment in Older Patients with Chronic Obstructive Pulmonary Disease by Using a Cognitive Functional Assessment Tool via a Touchscreen Personal Computer. Multidiscip Respir Med. 2022; (in press)
5. Hamada S, Togawa J, Sunadome H, Nagasaki T, Hirai T, Sato S. The Effects of Changing Continuous Positive Airway Pressure Devices in Japanese Patients with Obstructive Sleep Apnea: A Case Series. Internal Med 2022;0403–22. doi:10.2169/internalmedicine.0403-22.
6. Sato S, Miyazaki S, Tamaki A, Yoshimura Y, Arai H, Fujiwara D, Katsura H, Kawagoshi A, Kozu R, Maeda K, Ogawa S, Ueki J, Wakabayashi H. Respiratory sarcopenia: A position paper by four professional organizations. Geriatr Gerontol Int 2022; (in press) https://doi.org/10.1111/ggi.14519
7. Matsumoto T, Murase K, Tabara Y, Minami T, Kanai O, Takeyama H, Sunadome H, Nagasaki T, Takahashi N, Nakatsuka Y, Hamada S, Handa T, Tanizawa K, Nakamoto I, Wakamura T, Komenami N, Setoh K, Kawaguchi T, Tsutsumi T, Morita S, Takahashi Y, Nakayama T, Sato S, Hirai T, Matsuda F, Chin K. Sleep disordered breathing and hemoglobin A1c levels within or over normal range and aging or sex differences; the Nagahama Study. J Sleep Res 2022; Nov 27:e13795. (in press) doi: 10.1111/jsr.13795. Epub ahead of print.
8. Maetani T, Tanabe N, Terada S, Shiraishi Y, Shima H, Kaji S, Sakamoto R, Oguma T, Sato S, Masuda I, Hirai T. Physiological impacts of computed tomography airway dysanapsis, fractal dimension and branch count in asymptomatic never smokers. J Appl Physiol 2023;134:20–27. doi: 10.1152/japplphysiol.00385.2022.
9. Mochizuki F, Tanabe N, Iijima H, Shimada T, Shiraishi Y, Maetani T, Yamazaki H, Shimizu K, Suzuki M, Chubachi S, Ishikawa H, Naito T, Masuko H, Sakamoto T, Masuda I, Sato S, Hizawa N, Hirai T. Early Chronic Obstructive Pulmonary Disease: Associations of Two Spirometry Criteria with Clinical Features. Respir Med 2022;204:107011. https://doi.org/10.1016/j.rmed.2022.107011
10. Oguma A, Shimizu K, Kimura H, Tanabe N, Sato S, Yokota I, Sato M, Abe Y, Takei N, Matsumoto-Sasaki M, Goudarzi H, Suzuki M, Makita H, Hirai T, Nishimura M, Konno S. Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation. Allergol Int 2022; (in press) https://doi.org/10.1016/j.alit.2022.10.007
11. Hamada R, Sato S, Miyasaka J, Murao M, Masudhita M, Tajimoto T, Otagaki A, Asano T, Nangaku M, Kondo T, Arai Y, Kanda J, Takanori-Kondo A, Ikeguchi R, Matsuda S. Belt electrode-skeletal muscle electrical stimulation during early hematopoietic post-transplantation to prevent skeletal muscle atrophy and weakness. Transplant Cell Ther 2022; (in press) doi.org/10.1016/j.jtct.2022.09.030
12. Maetani T, Tanabe N, Shiraishi Y, Shimada Tm Terada S, Shima H, Mochizuki F, Sakamoto R, Kaji S, Oguma T, Sato S, Iijima H, Masuda I, Hirai T. Centrilobular emphysema is associated with pectoralis muscle reduction in current smokers without airflow limitation. Respiration 2022; (in press)
13. Tanabe N, Masuda I, Shiraishi Y, Maetani T, Hamada S, Sato A, Sato S, Hirai T. Clinical relevance of multiple confirmed preserved ratio impaired spirometry in adults. Respir Investig 2022;60:822–830. doi:10.1016/j.resinv.2022.08.006
14. Yoshioka Y, Oshima Y, Hata K, Sato S, Hamad R, Sato T, Kaido T, Munekage F, Ito T, Ikeguchi R, Uemoto S, Hatano E, Matsuda S. Factors Associated with Early Postoperative Exercise Tolerance after Living-Donor Liver Transplantation. Clin Transplant 2022; 2022;e14800. https://doi.org/10.1111/ctr.14800
15. Ejima A, Abe S, Shimba A, Sato S, Uehata T, Tani-ichi S, Munakata S, Cui G, Takeuchi O, Hirai T, Kato S, Ikuta K. Androgens alleviate allergic airway inflammation by suppressing cytokine production in Th2 cells. J Immunol 2022;209:1083–1094. https://doi.org/10.4049/jimmunol.2200294
16. Nagata K, Horie T, Chohnabayashi N, Jinta T, Tsugitomi R, Shiraki A, Tokioka F, Kadowaki T, Watanabe A, Fukui M, Kitajima T, Sato S, Tsuda T, Kishimoto N, Kita H, Mori Y, Nakayama M, Takahashi K, Tsuboi T, Yoshida M, Hataji O, Fuke S, Kagajo M, Nishine H, Kobayashi H, Nakamura H, Okuda M, Tachibana S, Takata S, Osoreda H, Minami K, Nishimura T, Ishida T, Terada J, Takeuchi N, Kohashi Y, Inoue H, Nakagawa Y, Kikuchi T, Tomii K, FLOCOP study investigators Home High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic COPD: A Randomized Trial. Am J Respir Crit Care Med 2022; 206:1326–1335. doi: 10.1164/rccm.202201-0199OC
17. Shima H, Tanabe N, Oguma A, Shimizu K, Kaji S, Terada K, Oguma T, Kubo T, Suzuki M, Makita H, Sato A, Nishimura M, Sato S, Konno S, Hirai T. Subtyping emphysematous COPD by respiratory volume change distributions on computed tomography. Thorax 2022:thoraxjnl-2021-218288. doi:10.1136/thoraxjnl-2021-218288
18. Hamakawa Y, Sato S, Tanabe N, Rhee CK, Jung KS, Yoo K-H, Tanimura K, Muro S, Hirai T. Non-respiratory symptom dominance is associated with depression in patients with chronic obstructive pulmonary disease. Respir Med 2022;201:106895. doi:10.1016/j.rmed.2022.106895
19. Shiraishi Y, Shimada T, Tanabe N, Terada K, Sakamoto R, Maetani T, Shima H, Mochizuki F, Oguma T, Shimizu K, Sato S, Muro S, Hizawa N, Fukui M, Iijima H, Masuda I, Hirai T. The prevalence and physiological impacts of centrilobular and paraseptal emphysema on CT in smokers with Preserved Ratio Impaired Spirometry. ERJ Open Res 2022 Jun 27;8(2):00063-2022. doi: 10.1183/23120541.00063-2022
20. Koda T, Sakamoto T, Wu S, Okumura S, Taki H, Hamada S, Sato S, Chin K. Comparison of Machine Learning and Non-machine Learning Methods for the Sleep Apnea Detection Using Millimeter-wave Radar. IEICE Com Exp 2022;2022XBL0050. https://doi.org/10.1587/comex.2022XBL0050
21. Sato T, Sato S, Oshima Y, Yoshioka Y, Hamada R, Nankaku M, Ikeda M, Nakajima D, Chen-Yoshikawa TF, Date H, Matsuda S, Tabira K. Impact of inspiratory muscle strength on exercise capacity after lung transplantation. Physiother Res Int 2022 Jul;27(3):e1951. doi: 10.1002/pri.1951
22. Hamakawa Y, Tanabe N, Shima H, Terada K, Shiraishi Y, Maetani T, Kubo T, Kozawa S, Koizumi K, Kanezaki M, Shimizu K, Oguma T, Sato A, Sato S, Hirai T. Pulmonary and extrapulmonary computed tomographic features in symptomatic and physically inactive patients with chronic obstructive pulmonary disease. Sci Rep 2022;12:5608. doi: 10.1038/s41598-022-09554-6
23. Kimura H, Shimizu K, Tanabe N, Makita H, Taniguchi N, Kimura H, Suzuki M, Abe Y, Matsumoto-Sasaki M, Oguma A, Takimoto-Sato M, Takei N, Matsumoto M, Goudarzi H, Sato S, Ono J, Izuhara K, Hirai T, Nishimura M, Konno S. Further evidence for association of YKL-40 with severe asthma airway remodeling. Ann Allergy Asthma Immunol 2022;128:682-688.e5. doi:10.1016/j.anai.2022.03.016
24. Zhang Y, Tanabe N, Shima H, Shiraishi Y, Oguma T, Sato A, Muro S, Sato S, Hirai T. Physiological impairments on respiratory oscillometry and future exacerbations in chronic obstructive pulmonary disease patients without a history of frequent exacerbations. COPD 2022;19(1):149-157. doi: 10.1080/15412555.2022.2051005.
25. Fukuyama K, Sugiyama O, Chin K, Sato S, Matsumoto S, Muto M. Identification of Respiratory Sounds Collected from Microphones Embedded in Mobile Phones. Adv Biomed Eng 2022;11:58–67. https://doi.org/10.14326/abe.11.58
26. Hamada S, Handa T, Tanabe N, Sato S, Tanizawa K, Sato A, Morita S, Chin K, Hirai T. Accuracy of respiratory rate surveillance using a home oxygen monitoring device among patients with interstitial lung disease and chronic obstructive pulmonary disease: Accuracy of home oxygen monitoring devices. Sarcoidosis VDLD 2022; 39: e2022007. doi: 10.36141/svdld.v39i1.12133.
27. Tanabe N, Kaji S, Shima H, Shiraishi Y, Maetani T, Oguma T, Sato S, Hirai T. Kernel conversion for robust quantitative measurements of archived chest computed tomography using deep learning-based image-to-image translation. Front Artif Intell 2022;4:769557. https://doi.org/10.3389/frai.2021.769557.
28. Ajimizu H, Ozasa H, Sato S, Funazo T, Sakamori Y, Nomizo T, Kuninaga K, Ogimoto T, Hosoya K, Yamazoe M, Tsuji T, Yoshida H, Itotani R, Ueno K, Kim YH, Muro S, Hirai T. Survival impact of treatment for chronic obstructive pulmonary disease in patients with advanced non-small-cell lung cancer. Sci Rep 2021;11:23677. https://doi.org/10.1038/s41598-021-03139-5.
29. Abe Y, Suzuki M, Shima H, Shiraishi Y, Tanabe N, Sato S, Shimizu K, Kimura H, Makita H, Hirai T, Konno S, Nishimura M. Annual Body Weight Change and Prognosis in Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis 2021;16:3243-3253. doi:10.2147/copd.s338908
30. Ibaraki T, Tomoda K, Fujioka N, Sakaguchi K, Fujita Y, Yamamoto Y, Hontsu S, Yamauchi M, Yoshikawa M, Tanabe N, Tanimura K, Sato S, Saeki K, Muro S. Fractal dimension in CT low attenuation areas is predictive of long-term oxygen therapy initiation in COPD patients: Results from two observational cohort studies. Respir Investig 2022;60(1):137–145. doi:10.1016/j.resinv.2021.09.001.
31. Hamada R, Oshima Y, Sato S, Yoshioka Y, Nankaku M, Kondo T, Chen-Yoshikawa TF, Ikeguchi R, Nakajima D, Date H, Matsuda S. Changes in the health-related quality of life and social reintegration status after lung transplantation following hematopoietic stem cell transplantation. Support Care Cancer 2022;30:1831–1839. doi:10.1007/s00520-021-06592-0.
32. Oshima Y, Sato S, Chen-Yoshikawa TF, Nakajima D, Nankaku M, Date H, Matsuda S. Erector spinae muscle radiographic density is associated with survival after lung transplantation. J Thorac Cardiovasc Surg 2022;164:300-311.e3. doi:10.1016/j.jtcvs.2021.07.039.
33. Shimizu K, Tanabe N, Oguma A, Kimura H, Suzuki M, Yokota I, Makita H, Sato S, Hirai T, Nishimura M, Konno S, The Hi-CARAT investigators. Parenchymal destruction in asthma: Fixed airflow obstruction and lung function trajectory. J Allergy Clin Immun 2022;149(3):934-942.e8. doi: 10.1016/j.jaci.2021.07.042.
34. Takahashi N, Matsumoto T, Nakatsuka Y, Murase K, Tabara Y, Takeyama H, Minami T, Hamada S, Kanai O, Tanizawa K, Nakamoto I, Kawaguchi T, Setoh K, Tsutsumi T, Takahashi Y, Handa T, Wakamura T, Komenami N, Morita S, Hirai T, Matsuda F, Nakayama T, Chin K; Nagahama Study Group. Differences between subjective and objective sleep duration according to actual sleep duration and sleep-disordered breathing: the Nagahama Study. J Clin Sleep Med 2022;18(3):851-859. doi: 10.5664/jcsm.9732.
35. Murase K, Minami T, Hamada S, Gozal D, Takahashi N, Nakatsuka Y, Takeyama H, Tanizawa K, Endo D, Akahoshi T, Moritsuchi Y, Tsuda T, Toyama Y, Ohi M, Tomita Y, Narui K, Matsuyama N, Ohdaira T, Kasai T, Tsuboi T, Gon Y, Yamashiro Y, Ando S, Yoshimine H, Takata Y, Yoshihisa A, Tatsumi K, Momomura S-I, Kuroda T, Morita S, et al. Multimodal Telemonitoring for Weight Reduction in Patients With Sleep Apnea: A Randomized Controlled Trial. Chest 2022; 162: 1373–1383.
36. Murase K, Matsumoto T, Tabara Y, Ohler A, Gozal D, Minami T, Kanai O, Takeyama H, Takahashi N, Hamada S, Tanizawa K, Wakamura T, Komenami N, Setoh K, Kawaguchi T, Tsutsumi T, Morita S, Takahashi Y, Nakayama T, Yanagita M, Hirai T, Matsuda F, Chin K. Association of Sleep-disordered Breathing and Blood Pressure with Albuminuria: The Nagahama Study. Ann Am Thorac Soc 2022;19:451–461.
2021年度
1. Ajimizu H, Ozasa H, Sato S, Funazo T, Sakamori Y, Nomizo T, Kuninaga K, Ogimoto T, Hosoya K, Yamazoe M, Tsuji T, Yoshida H, Itotani R, Ueno K, Kim YH, Muro S, Hirai T. Survival impact of treatment for chronic obstructive pulmonary disease in patients with advanced non-small-cell lung cancer. Sci Rep 2021;11:23677.
2. Abe Y, Suzuki M, Shima H, Shiraishi Y, Tanabe N, Sato S, Shimizu K, Kimura H, Makita H, Hirai T, Konno S, Nishimura M. Annual Body Weight Change and Prognosis in Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis 2021 Nov 30;16:3243-3253.
3. Ibaraki T, Tomoda K, Fujioka N, Sakaguchi K, Fujita Y, Yamamoto Y, Hontsu S, Yamauchi M, Yoshikawa M, Tanabe N, Tanimura K, Sato S, Saeki K, Muro S. Fractal dimension in CT low attenuation areas is predictive of long-term oxygen therapy initiation in COPD patients: Results from two observational cohort studies. Respir Investig 2022;60(1):137–145.
4. Tanabe N, Sakamoto R, Kozawa S, Oguma T, Shima H, Shiraishi Y, Koizumi K, Sato S, Nakamoto Y, Hirai T. Deep learning-based reconstruction of chest ultra-high-resolution computed tomography and quantitative evaluations of smaller airways. Respir Investig 2021;60(1):167–170.
5. Hamada R, Oshima Y, Sato S, Yoshioka Y, Nankaku M, Kondo T, Chen-Yoshikawa TF, Ikeguchi R, Nakajima D, Date H, Matsuda S. Changes in the health-related quality of life and social reintegration status after lung transplantation following hematopoietic stem cell transplantation. Support Care Cancer 2022;30:1831–1839.
6. Oshima Y, Sato S, Chen-Yoshikawa TF, Nakajima D, Nankaku M, Date H, Matsuda S. Erector spinae muscle radiographic density is associated with survival after lung transplantation. J Thorac Cardiovasc Surg 2021;1–48. (Journal Pre-Proof)
7. Kanezaki M, Terada K, Tanabe N, Shima H, Hamakawa Y, Sato S. Exertional multidimensional dyspnoea predicts exacerbation in stable outpatients with COPD. ERJ Open Res 2021;00150–02021.
8. Shimizu K, Tanabe N, Oguma A, Kimura H, Suzuki M, Yokota I, Makita H, Sato S, Hirai T, Nishimura M, Konno S, The Hi-CARAT investigators. Parenchymal destruction in asthma: Fixed airflow obstruction and lung function trajectory. J Allergy Clin Immun 2022;149(3):934-942.e8.
9. Kogo M, Matsumoto H, Tanabe N, Chen-Yoshikawa TF, Nakajima N, Yoshizawa A, Oguma T, Sato S, Nomura N, Morimoto C, Sunadome H, Gotoh S, Ohsumi A, Date H, Hirai T. The importance of central airway dilatation in patients with bronchiolitis obliterans. ERJ Open Res 2021;7:00123–02021.
10. Hamada R, Oshima Y, Sato S, Yoshioka Y, Sato T, Nankaku M, Kondo T, Chen-Yoshikawa TF, Ikeguchi R, Nakajima D, Date H, Matsuda S. Physical function after lung transplantation for late-onset noninfectious pulmonary complications after allogeneic hematopoietic stem cell transplantation. Support Care Cancer 2021;29:5447–5454.
11. Tanabe N, Kaji S, Sato S, Yokoyama T, Oguma T, Tanizawa K, Handa T, Sakajo T, Hirai T. A homological approach to a mathematical definition of pulmonary fibrosis and emphysema on computed tomography. J Appl Physiol 2021;131:601–612.
12. Tanabe N, Sato S, Oguma T, Shima H, Kubo T, Kozawa S, Koizumi K, Sato A, Togashi K, Matsumoto H, Hirai T. Influence of Asthma Onset on Airway Dimensions on Ultra-high-resolution Computed Tomography in Chronic Obstructive Pulmonary Disease. J Thorac Imaging 2021;36:224–230.
13. Tanabe N, Shima H, Sato S, Hirai T. Reply to: What is “functional small airway disease” in inspiratory and expiratory CT images? Respir Investig 2021;59:564–565.
14. Tanabe N, Terada K, Shima H, Hamakawa Y, Shiraishi Y, Shimizu K, Sato A, Oguma T, Sato S, Hirai T. Expiratory central airway collapse and symptoms in smokers. Respir Investig 2021;59:522–529.
15. Takei N, Suzuki M, Tanabe N, Oguma A, Shimizu K, Kimura H, Makita H, Sato S, Hirai T, Yokota I, Konno S, Nishimura M. Combined assessment of pulmonary arterial enlargement and coronary calcification predicts the prognosis of patients with chronic obstructive pulmonary disease. Respir Med 2021;185:106520.
16. Tanabe N, Sato S. Narrative review of current COPD status in Japan. J Thorac Dis 2021;13:3878–3887.
17. Kanezaki M, Terada K, Tanabe N, Shima H, Hamakawa Y, Sato S. Effects of Sarcopenia on Ventilatory Behavior and the Multidimensional Nature of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc 2021;22:827–833.
18. Tanabe N, Sato S, Tanimura K, Oguma T, Sato A, Muro S, Hirai T. Associations of CT evaluations of antigravity muscles, emphysema and airway disease with longitudinal outcomes in patients with COPD. Thorax 2021;76:295–297.
19. Sunadome H, Sato S, Matsumoto H, Murase K, Kawaguchi T, Tabara Y, Chin K, Matsuda F, Hirai T. Similar distribution of peripheral blood eosinophil counts in European and East Asian populations from investigations of large-scale general population studies: the Nagahama Study. Eur Respir J 2021;57:2004101.
20. Koshiyama S, Tanimura K, Ito K, Funayama S, Hira D, Komase Y, Sato S. Gastroesophageal reflux-like symptoms are associated with hyposalivation and oropharyngeal problems in patients with asthma. Respir Investig 2021;59:114–119.
21. Tanabe N, Shimizu K, Terada K, Sato S, Suzuki M, Shima H, Oguma A, Oguma T, Konno S, Nishimura M, Hirai T. Central airway and peripheral lung structures in airway disease dominant COPD. ERJ Open Res 2021;7:00672–2020.
22. Sukeishi A, Itohara K, Yonezawa A, Sato Y, Matsumura K, Katada Y, Nakagawa T, Hamada S, Tanabe N, Imoto E, Kai S, Hirai T, Yanagita M, Ohtsuru S, Terada T, Ito I. Population pharmacokinetic modeling of GS-441524, the active metabolite of remdesivir, in Japanese COVID-19 patients with renal dysfunction. Cpt Pharmacometrics Syst Pharmacol 2022;11:94–103.
23. Hamada S, Tanabe N, Inoue H, Hirai T. Is high-flow nasal cannula oxygen therapy an aerosol-generating medical procedure? Archivos De Bronconeumología 2021;57:601–602.
24. Hamada S, Tanabe N, Hirai T. Effects of combined oxygen and surgical masks on inspired fraction of oxygen: relevance to COVID-19-induced repiratory failure. Brit J Anaesth 2021;126:e215–e217.
25. Xu F, Tanabe N, Vasilescu DM, McDonough JE, Coxson HC, Ikezoe K, Kinose D, Ng KW, Verleden SE, Wuyts WA, Vanaudenaerde BM, Verschakelen J, Cooper JD, Lenburg ME, Morshead KB, Abbas AR, Arron JR, Spira A, Hackett T-L, Colby TV, Ryerson CJ, Ng RT, Hogg JC. The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF). Ebiomedicine 2021;66:103325.
26. Shirata M, Ito I, Tanabe N, Konishi S, Oi I, Hamao N, Matsumoto H, Yasutomo Y, Kadowaki S, Hirai T. Risk factors associated with methicillin-resistant Staphylococcus aureus isolation from serially collected sputum samples of patients hospitalized with pneumonia. J Infect Chemother 2021;27:1323–1328.
27. Hamada S, Tanabe N, Hirai T. Speech Sounds and the Production of Droplets and Aerosols. Internal medicine (Tokyo, Japan) 2020;5888–20.
28. Oi I, Ito I, Hirabayashi M, Endo K, Emura M, Kojima T, Tsukao H, Tomii K, Nakagawa A, Otsuka K, Akai M, Oi M, Sugita T, Fukui M, Inoue D, Hasegawa Y, Takahashi K, Yasui H, Fujita K, Ishida T, Ito A, Kita H, Kaji Y, Tsuchiya M, Tomioka H, Yamada T, Terada S, Nakaji H, Hamao N, et al. Pneumonia Caused by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Virus: A Multicenter Comparative Study. Open Forum Infect Dis 2021;8:ofab282-.
29. Hamada S, Tanabe N, Hirai T. Humidification via high-flow nasal cannula oxygen therapy does not generate aerosols. Brit J Anaesth 2021;127:e109–e110.
30. Ikezoe K, Hackett T-L, Peterson S, Prins D, Hague CJ, Murphy D, LeDoux S, Chu F, Xu F, Cooper JD, Tanabe N, Ryerson CJ, Paré PD, Coxson HO, Colby TV, Hogg JC, Vasilescu DM. Small Airway Reduction and Fibrosis Is an Early Pathologic Feature of Idiopathic Pulmonary Fibrosis. Am J Resp Crit Care 2021;204:1048–1059.
31. Handa T, Tanizawa K, Oguma T, Uozumi R, Watanabe K, Tanabe N, Niwamoto T, Shima H, Mori R, Nobashi TW, Sakamoto R, Kubo T, Kurosaki A, Kishi K, Nakamoto Y, Hirai T. Novel Artificial Intelligence-based Technology for Chest Computed Tomography Analysis of Idiopathic Pulmonary Fibrosis. Ann Am Thorac Soc 2021;doi:10.1513/annalsats.202101-044oc.
32. Kirby M, Smith BM, Tanabe N, Hogg JC, Coxson HO, Sin DD, Bourbeau J, Tan WC. Computed tomography total airway count predicts progression to COPD in at-risk smokers. ERJ Open Res 2021;7:00307–02021.
33. Xu F, Vasilescu DM, Kinose D, Tanabe N, Ng KW, Coxson HO, Cooper JD, Hackett T-L, Verleden SE, Vanaudenaerde BM, Stevenson CS, Lenburg ME, Spira A, Tan WC, Sin DD, Ng RT, Hogg JC. The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in chronic obstructive pulmonary disease. Eur Respir J 2021;2101411.
2020年度
1. Tanabe N, Sato S, Tanimura K, Oguma T, Sato A, Muro S, Hirai T. Associations of CT evaluations of antigravity muscles, emphysema and airway disease with longitudinal outcomes in patients with COPD. Thorax. 2021;76:295-297. (Publish ahead of print, Aug 2020)
2. Koshiyama S, Tanimura K, Ito K, Funayama S, Hira D, Komase Y, Sato S. Gastroesophageal reflux-like symptoms are associated with hyposalivation and oropharyngeal problems in patients with asthma. Respir Investig 2021;59:114–119. (Published on line, July 2020)
3. Tanabe N*, Sato S*, Suki B, Hirai T. Fractal Analysis of Lung Structure in Chronic Obstructive Pulmonary Disease. Front Physiol; 2020 Dec 21;11:1–12.
4. Tanabe N, McDonough JE, Vasilescu DM, Ikezoe K, Verleden SE, Xu F, Wuyts WA, Vanaudenaerde BM, Colby TV, Hogg JC. Pathology of Idiopathic Pulmonary Fibrosis Assessed by a Combination of Microcomputed Tomography, Histology, and Immunohistochemistry. Am J Pathol 2020;190:2427–2435.
5. Hamada S, Tanabe N, Hirai T. Speech Sounds and the Production of Droplets and Aerosols. Intern Med 2020;5888–20.doi:10.2169/internalmedicine.5888-20.
6. Tanabe N, Rhee CK, Sato S, Muro S, Shima H, Tanimura K, Jung KS, Yoo K-H, Hirai T. Disproportionally Impaired Diffusion Capacity Relative to Airflow Limitation in COPD. COPD. 2020; 17(6):627–34.
7. Tanabe N, Matsumoto H, Hamada S, Ito I, Hirai T. Dupilumab maintenance therapy in an asthmatic patient with coronavirus disease 2019 pneumonia. Allergol Int 2020;doi:10.1016/j.alit.2020.10.005.
8. Tanabe N, Sato S, Oguma T, Shima H, Kubo T, Kozawa S, Koizumi K, Sato A, Togashi K, Matsumoto H, Hirai T. Influence of Asthma Onset on Airway Dimensions on Ultra-high-resolution Computed Tomography in Chronic Obstructive Pulmonary Disease. J Thorac Imaging. 2020 Nov 4;Publish Ahead of Print.
9. Vameghestahbanati M, Kirby M, Tanabe N, Vasilescu DM, Janssens W, Everaerts S, Vanaudenaerde BM, Benedetti A, Hogg JC, Smith BM. Central Airway Tree Dysanapsis Extends to the Peripheral Airways. Am J Respir Crit Care Med 2020;rccm.202007–3025LE.doi:10.1164/rccm.202007-3025LE.
10. Tanabe N, Vasilescu DM, Hague CJ, Ikezoe K, Murphy DT, Kirby M, Stevenson CS, Verleden SE, Vanaudenaerde BM, Gayan-Ramirez G, Janssens W, Coxson HO, Paré PD, Hogg JC. Pathological Comparisons of Paraseptal and Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2020;202:803–811.
11. Oishi A, Noda K, Birtel J, Miyake M, Sato A, Hasegawa T, Miyata M, Numa S, Charbel Issa P, Tsujikawa A. Effect of smoking on macular function and retinal structure in retinitis pigmentosa. Brain Commun 2020;2:fcaa117.
12. Tanimura K, Sato S, Sato A, Tanabe N, Hasegawa K, Uemasu K, Hamakawa Y, Hirai T, Muro S. Low serum free light chain is associated with risk of COPD exacerbation. ERJ Open Res. 2020; 6(2):00288–2019.
13. Oshima Y, Sato S, Chen-Yoshikawa TF, Yoshioka Y, Shimamura N, Hamada R, Nankaku M, Tamaki A, Date H, Matsuda S. Quantity and quality of antigravity muscles in patients undergoing living-donor lobar lung transplantation: 1-year longitudinal analysis using chest computed tomography images. ERJ Open Res. 2020; 6(2):00205–2019.
14. Sakaguchi Y, Matsumoto K, Nishioka K, Iizuka N, Hirayama Y, Kitaoka A, Tanimura K, Takahashi KI, Kato M. Bronchoscopic Surgery for a Solitary Tracheal Tumor of Tracheobronchopathia Osteochondroplastica. Ann Thorac Surg 2020;109(6):e419-e421.
15. Hamao N, Ito I, Konishi S, Tanabe N, Shirata M, Oi I, Tsukino M, Matsumoto H, Yasutomo Y, Kadowaki S, Hirai T. Comparison of ceftriaxone plus macrolide and ampicillin/sulbactam plus macrolide in treatment for patients with community-acquired pneumonia without risk factors for aspiration: an open-label, quasi-randomized, controlled trial. BMC Pulm Med 2020;20:160–11.
16. Tanimura K, Sato S, Sato A, Tanabe N, Hasegawa K, Uemasu K, Hamakawa Y, Oguma T, Muro S, Hirai T. Accelerated Loss of Antigravity Muscles Is Associated with Mortality in Patients with COPD. Respiration 2020; 99: 298–306.
17. Verleden SE, Tanabe N, McDonough JE, Vasilescu DM, Xu F, Wuyts WA, Piloni D, De Sadeleer L, Willems S, Mai C, Hostens J, Cooper JD, Verbeken EK, Verschakelen J, Galbán CJ, van Raemdonck DE, Colby TV, Decramer M, Verleden GM, Kaminski N, Hackett T-L, Vanaudenaerde BM, Hogg JC. Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study. Lancet Respir Med 2020;8:573–584.
18. Kirby M, Tanabe N, Vasilescu DM, Cooper JD, McDonough JE, Verleden SE, Vanaudenaerde BM, Sin DD, Tan WC, Coxson HO, Hogg JC. Computed Tomography Total Airway Count Is Associated with the Number of Micro-Computed Tomography Terminal Bronchioles. Am J Respir Crit Care Med 2020;201:613–615.
19. Tam A, Tanabe N, Churg A, Wright JL, Hogg JC, Sin DD. Sex differences in lymphoid follicles in COPD airways. Respir Res 2020;21:46–13.
20. Oi I, Ito I, Tanabe N, Konishi S, Hamao N, Yasutomo Y, Kadowaki S, Hirai T. Cefepime vs. meropenem for moderate-to-severe pneumonia in patients at risk for aspiration: An open-label, randomized study. J Infect Chemother 2020;26:181–187.
21. Shimizu K, Tanabe N, Tho NV, Suzuki M, Makita H, Sato S, Muro S, Mishima M, Hirai T, Ogawa E, Nakano Y, Konno S, Nishimura M. Per cent low attenuation volume and fractal dimension of low attenuation clusters on CT predict different long-term outcomes in COPD. Thorax 2020; 75: 116–122.
22. Shima H, Tanabe N, Sato S, Oguma T, Kubo T, Kozawa S, Koizumi K, Watanabe A, Sato A, Togashi K, Hirai T. Lobar distribution of non-emphysematous gas trapping and lung hyperinflation in chronic obstructive pulmonary disease. Respir Investig 2020; 58: 246–254.
2019年
1. Tanabe N, Sato S, Muro S, Shima H, Oguma T, Tanimura K, Sato A, Hirai T. Regional lung deflation with increased airway volume underlies the functional response to bronchodilators in chronic obstructive pulmonary disease. Physiol Rep. 2019 Dec 26;7(24):263–9.
2. McDonough JE, Ahangari F, Li Q, Jain S, Verleden SE, Herazo-Maya J, Vukmirovic M, DeIuliis G, Tzouvelekis A, Tanabe N, Chu F, Yan X, Verschakelen J, Homer RJ, Manatakis DV, Zhang J, Ding J, Maes K, De Sadeleer L, Vos R, Neyrinck A, Benos PV, Bar-Joseph Z, Tantin D, Hogg JC, Vanaudenaerde BM, Wuyts WA, Kaminski N. Transcriptional regulatory model of fibrosis progression in the human lung. JCI Insight. 2019 Nov 14;4(22):67.
3. Kirby M, Tanabe N, Vasilescu DM, Cooper JD, McDonough JE, Verleden SE, Vanaudenaerde BM, Sin DD, Tan WC, Coxson HO, Hogg JC. Computed Tomography Total Airway Count is Associated with Number of Micro-CT Terminal Bronchioles. Am J Respir Crit Care Med. 2019 Nov 7;:rccm.201910–1948LE.
4. Tanabe N, Shima H, Sato S, Oguma T, Kubo T, Kozawa S, Koizumi K, Sato A, Togashi K, Hirai T. Direct evaluation of peripheral airways using ultra-high-resolution CT in chronic obstructive pulmonary disease. Eur J Radiol. 2019 Sep 20;120:108687.
5. Mochizuki F, Iijima H, Watanabe A, Tanabe N, Sato S, Shiigai M, Fujiwara K, Shimada T, Ishikawa H, Kanazawa J, Yatagai Y, Masuko H, Sakamoto T, Muro S, Hizawa N. The Concavity of the Maximal Expiratory Flow-Volume Curve Reflects the Extent of Emphysema in Obstructive Lung Diseases. Sci Rep. 2019 Sep 11;9(1):13159.
6. Vasilescu DM, Martinez FJ, Marchetti N, Galbán CJ, Hatt C, Meldrum CA, Dass C, Tanabe N, Reddy RM, Lagstein A, Ross BD, Labaki WW, Murray S, Meng X, Curtis JL, Hackett TL, Kazerooni EA, Criner GJ, Hogg JC, Han MK. Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2019 Sep 1;200(5):575–81.
7. Oshima A, Nishimura A, Chen-Yoshikawa TF, Harashima S-I, Komatsu T, Handa T, Aoyama A, Takahashi K, Ikeda M, Oshima Y, Ikezoe K, Sato S, Isomi M, Shide K, Date H, Inagaki N. Nutrition-related factors associated with waiting list mortality in patients with interstitial lung disease: A retrospective cohort study. Clin Transplant. 2019 Jun;33(6):e13566.
8. Tanabe N, Sato S, Oguma T, Shima H, Sato A, Muro S, Hirai T. Associations of airway tree to lung volume ratio on computed tomography with lung function and symptoms in chronic obstructive pulmonary disease. Respir Res. BioMed Central; 2019 Apr 18;20(1):77.
9. Uemasu K, Sato S, Muro S, Sato A, Tanabe N, Hasegawa K, Hamakawa Y, Mizutani T, Fuseya Y, Tanimura K, Takahashi T, Hirai T. Annual decline in arterial blood oxygen predicts development of chronic respiratory failure in COPD with mild hypoxaemia: A 6-year follow-up study. Respirology. 2019 Mar;24(3):262–9.
10. Fuseya Y, Muro S, Sato S, Sato A, Tanimura K, Hasegawa K, Uemasu K, Hamakawa Y, Takahashi Y, Nakayama T, Sakai N, Fukui M, Kita H, Mio T, Mishima M, Hirai T. Perspectives on End-of-Life Treatment among Patients with COPD: A Multicenter, Cross-sectional Study in Japan. COPD. 2019 Feb;16(1):75–81.  Mondoñedo JR, Sato S, Oguma T, Muro S, Sonnenberg AH, Zeldich D, Parameswaran H, Hirai T, Suki B. CT Imaging-Based Low-Attenuation Super Clusters in Three Dimensions and the Progression of Emphysema. Chest. 2019 Jan;155(1):79–87.
2018年
1. Fuseya Y, Muro S, Sato S, Tanabe N, Sato A, Tanimura K, Hasegawa K, Uemasu K, Kubo T, Kido A, Fujimoto K, Fushimi Y, Kusahara H, Sakashita N, Ohno Y, Togashi K, Mishima M, Hirai T. Complementary regional heterogeneity information from COPD patients obtained using oxygen-enhanced MRI and chest CT. Vij N, ed. PLoS ONE. 2018;13(8):e0203273. doi:10.1371/journal.pone.0203273.
2. Yoshimura K, Sato S, Muro S, Yamada M, Hasegawa K, Kiyokawa H, Mishima M, Aoyama T. Interdependence of physical inactivity, loss of muscle mass and low dietary intake: Extrapulmonary manifestations in older chronic obstructive pulmonary disease patients. Geriatr Gerontol Int. 2018;18(1):88-94. doi:10.1111/ggi.13146.
3. Nagata K, Kikuchi T, Horie T, Shiraki A, Kitajima T, Kadowaki T, Tokioka F, Chohnabayashi N, Watanabe A, Sato S, Tomii K. Domiciliary High-Flow Nasal Cannula Oxygen Therapy for Patients with Stable Hypercapnic Chronic Obstructive Pulmonary Disease. A Multicenter Randomized Crossover Trial. Ann Am Thorac Soc. 2018;15(4):432-439. doi:10.1513/AnnalsATS.201706-425OC.
4. Hasegawa K, Sato S, Tanimura K, Fuseya Y, Uemasu K, Hamakawa Y, Sato A, Mishima M, Muro S, Hirai T. Gastroesophageal reflux symptoms and nasal symptoms affect the severity of bronchitis symptoms in patients with chronic obstructive pulmonary disease. Respir Investig. 2018;56(3):230-237. doi:10.1016/j.resinv.2018.01.001.
5. Ito J, Nagata K, Sato S, Shiraki A, Nishimura N, Izumi S, Tachikawa R, Morimoto T, Tomii K. The clinical practice of high-flow nasal cannula oxygen therapy in adults: A Japanese cross-sectional multicenter survey. Respir Investig. 2018;56(3):249-257. doi:10.1016/j.resinv.2018.02.002.
6. Shioya T, Sato S, Iwakura M, Takahashi H, Terui Y, Uemura S, Satake M. Improvement of physical activity in chronic obstructive pulmonary disease by pulmonary rehabilitation and pharmacological treatment. Respir Investig. 2018;56(4):292-306. doi:10.1016/j.resinv.2018.05.002.
7. Tanabe N, Muro S, Sato S, Oguma T, Sato A, Hirai T. Fractal analysis of low attenuation clusters on computed tomography in chronic obstructive pulmonary disease. BMC Pulm Med. 2018;18(1):144. doi:10.1186/s12890-018-0714-5.
8. Uemasu K, Sato S, Muro S, Sato A, Tanabe N, Hasegawa K, Hamakawa Y, Mizutani T, Fuseya Y, Tanimura K, Takahashi T, Hirai T. Annual decline in arterial blood oxygen predicts development of chronic respiratory failure in COPD with mild hypoxaemia: A 6-year follow-up study. Respirology. 2018;6:199. doi:10.1111/resp.13402.
9. Suzuki M, Muro S, Fukui M, Ishizaki N, Sato S, Shiota T, Endo K, Suzuki T, Mitsuma T, Mishima M, Hirai T. Effects of acupuncture on nutritional state of patients with stable chronic obstructive pulmonary disease (COPD): re-analysis of COPD acupuncture trial, a randomized controlled trial. BMC Complement Altern Med. 2018;18(1):287. doi:10.1186/s12906-018-2341-3.
10. Tanabe N, Oguma T, Sato S, Kubo T, Kozawa S, Shima H, Koizumi K, Sato A, Muro S, Togashi K, Hirai T. Quantitative measurement of airway dimensions using ultra-high resolution computed tomography. Respir Investig. 2018;56(6):489-496. doi:10.1016/j.resinv.2018.07.008.
11. Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO, CanCOLD Collaborative Research Group, Canadian Respiratory Research Network, CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network. Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study. Am J Respir Crit Care Med. 2018;197(1):56-65. doi:10.1164/rccm.201704-0692OC.
12. Tanabe N, Vasilescu DM, Kirby M, Coxson HO, Verleden SE, Vanaudenaerde BM, Kinose D, Nakano Y, Paré PD, Hogg JC. Analysis of airway pathology in COPD using a combination of computed tomography, micro-computed tomography and histology. Eur Respir J. 2018;51(2):1701245. doi:10.1183/13993003.01245-2017.
13. McDonough JE, Martens DS, Tanabe N, Ahangari F, Verleden SE, Maes K, Verleden GM, Kaminski N, Hogg JC, Nawrot TS, Wuyts WA, Vanaudenaerde BM. A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis. Respir Res. 2018;19(1):132. doi:10.1186/s12931-018-0838-4.
14. Mondoñedo JR, Sato S, Oguma T, Muro S, Sonnenberg AH, Zeldich D, Parameswaran H, Hirai T, Suki B. CT-Based Low-Attenuation Super Clusters in 3D and the Progression of Emphysema. Chest. October 2018. doi:10.1016/j.chest.2018.09.014.
2017年
1. Kamada T, Ito I, Kanemitsu Y, Sato S, Matsumoto H, Niimi A, Mishima M. Three-dimensional imaging forced oscillation technique to assess position-dependent airway obstruction in relapsing polychondritis: A case report. Respir Investig. 2017 Jan;55(1):69–73.
2. Vasilescu DM, Phillion AB, Tanabe N, Kinose D, Paige DF, Kantrowitz JJ, Liu G, Liu H, Fishbane N, Verleden SE, Vanaudenaerde BM, Lenburg M, Stevenson CS, Spira A, Cooper JD, Hackett T-L, Hogg JC. Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue. Journal of applied physiology. 2017 Jan 1;122(1):161–9.
3. Tanabe N, Vasilescu DM, McDonough JE, Kinose D, Suzuki M, Cooper JD, Paré PD, Hogg JC. Micro-Computed Tomography Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema. Am J Respir Crit Care Med. 2017 Mar 1;195(5):630–8.
4. Matsumoto T, Tabara Y, Murase K, Takahashi Y, Setoh K, Kawaguchi T, Muro S, Kadotani H, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda F, Chin K. Combined association of clinical and lifestyle factors with non-restorative sleep: The Nagahama Study. PLoS ONE. 2017;12(3):e0171849.
5. Sokai A, Tanizawa K, Handa T, Kubo T, Hashimoto S, Ikezoe K, Nakatsuka Y, Aihara K, Taguchi Y, Muro S, Oga T, Nagai S, Izumi T, Hirai T, Chin K, Mishima M. Asymmetry in acute exacerbation of idiopathic pulmonary fibrosis. ERJ Open Res. European Respiratory Society; 2017 Apr;3(2):00036–2016.
6. Matsumoto H, Izuhara Y, Niimi A, Tabara Y, Nagasaki T, Kanemitsu Y, Murase K, Oguma T, Ito I, Muro S, Sekine A, Matsuda F, Kosugi S, Nakayama T, Chin K, Mishima M, Nagahama Study Collaboration Group. Risks and Cough-Aggravating Factors in Prolonged Cough. Epidemiological Observations from the Nagahama Cohort Study. Ann Am Thorac Soc. 2017 May;14(5):698–705.
7. Nagami S, Oku Y, Yagi N, Sato S, Uozumi R, Morita S, Yamagata Y, Kayashita J, Tanimura K, Sato A, Takahashi R, Muro S. Breathing-swallowing discoordination is associated with frequent exacerbations of COPD. BMJ Open Respir Res. 2017 Jun 5;4(1):e000202–10.
8. Ikezoe K, Handa T, Tanizawa K, Yokoi H, Kubo T, Aihara K, Sokai A, Nakatsuka Y, Hashimoto S, Uemasu K, Sato S, Muro S, Nagai S, Yanagita M, Chin K, Hirai T, Taguchi Y, Mishima M. Chronic Kidney Disease Predicts Survival in Patients with Idiopathic Pulmonary Fibrosis. Respiration. 2017;94(4):346–54.
9. Yoshimura K, Sato S, Muro S, Yamada M, Hasegawa K, Kiyokawa H, Mishima M, Aoyama T. Interdependence of physical inactivity, loss of muscle mass and low dietary intake: Extrapulmonary manifestations in older chronic obstructive pulmonary disease patients. Geriatr Gerontol Int. 2017 Aug 4;187(1):347.
10. Hasegawa K, Sato A, Tanimura K, Uemasu K, Hamakawa Y, Fuseya Y, Sato S, Muro S, Hirai T. Fraction of MHCII and EpCAM expression characterizes distal lung epithelial cells for alveolar type 2 cell isolation. Respir Res. BioMed Central; 2017 Aug 7;18(1):150.
11. Yamamoto Y, Gotoh S, Korogi Y, Seki M, Konishi S, Ikeo S, Sone N, Nagasaki T, Matsumoto H, Muro S, Ito I, Hirai T, Kohno T, Suzuki Y, Mishima M. Long-term expansion of alveolar stem cells derived from human iPS cells in organoids. Nat Methods. Nature Publishing Group; 2017 Nov;14(11):1097–106.
12. Nagata K, Kikuchi T, Horie T, Shiraki A, Kitajima T, Kadowaki T, Tokioka F, Chohnabayashi N, Watanabe A, Sato S, Tomii K. Domiciliary High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic COPD Patients: A Multicenter, Randomized Crossover Trial. Ann Am Thorac Soc. 2017 Dec 28;:AnnalsATS.201706–425OC.
2016年
1. Shikuma K, Menju T, Chen F, Kubo T, Muro S, Sumiyoshi S, Ohata K, Sowa T,　Nakanishi T, Cho H, Neri S, Aoyama A, Sato T, Sonobe M, Date H. Is volumetric　3-dimensional computed tomography useful to predict histological tumour　invasiveness? Analysis of 211 lesions of cT1N0M0 lung adenocarcinoma. Interact　Cardiovasc Thorac Surg. 2016 Jun;22(6):831-8.
2. Tsao PN, Matsuoka C, Wei SC, Sato A, Sato S, Hasegawa K, Chen HK, Ling TY, Mori M, Cardoso WV, Morimoto M.　Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8242-7. doi: 10.1073/pnas.1511236113.
3. Hamada S, Sato A, Hara-Chikuma M, Satooka H, Hasegawa K, Tanimura K, Tanizawa K, Inouchi M, Handa T, Oga T, Muro S, Mishima M, Chin K.　 Role of mitochondrial hydrogen peroxide induced by intermittent hypoxia in airway epithelial wound repair in vitro.　Exp Cell Res. 2016 May 15;344(1):143-51. doi: 10.1016/j.yexcr.2016.04.006.
4. Muro S, Tabara Y, Matsumoto H, Setoh K, Kawaguchi T, Takahashi M, Ito I, Ito　Y, Murase K, Terao C, Kosugi S, Yamada R, Sekine A, Nakayama T, Chin K, Mishima　M, Matsuda F; Nagahama Study Group.. Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary　Disease in A General Japanese Population: The Nagahama Study. Medicine　(Baltimore). 2016 Apr;95(15):e3371.
5. Yi E, Sato S, Takahashi A, et al. Mechanical Forces Accelerate Collagen Digestion by Bacterial Collagenase in Lung Tissue Strips.Frontiers in Physiology. 2016;7:287. doi:10.3389/fphys.2016.00287.
2015年
1. Tanimura K, Sato S, Fuseya Y, Hasegawa K, Uemasu K, Sato A, Oguma T, Hirai T,
  Mishima M, Muro S. Quantitative Assessment of Erector Spinae Muscles in Patients
  with Chronic Obstructive Pulmonary Disease. Novel Chest Computed
  Tomography-derived Index for Prognosis. Ann Am Thorac Soc. 2016 Mar;13(3):334-41.
  doi: 10.1513/AnnalsATS.201507-446OC. PubMed PMID: 26700501.
2. Konishi S, Gotoh S, Tateishi K, Yamamoto Y, Korogi Y, Nagasaki T, Matsumoto H,
  Muro S, Hirai T, Ito I, Tsukita S, Mishima M. Directed Induction of Functional
  Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human
  Pluripotent Stem Cells. Stem Cell Reports. 2016 Jan 12;6(1):18-25. doi:
  10.1016/j.stemcr.2015.11.010. Epub 2015 Dec 24. PubMed PMID: 26724905; PubMed
  Central PMCID: PMC4720023.
3. Kinose D, Ogawa E, Kudo M, Marumo S, Kiyokawa H, Hoshino Y, Hirai T, Chin K,
  Muro S, Mishima M. Association of COPD exacerbation frequency with gene
  expression of pattern recognition receptors in inflammatory cells in induced
  sputum. Clin Respir J. 2016 Jan;10(1):11-21. doi: 10.1111/crj.12171. Epub 2014
  Aug 13. PubMed PMID: 24902764.
4. Sokai A, Handa T, Tanizawa K, Oga T, Uno K, Tsuruyama T, Kubo T, Ikezoe K,
  Nakatsuka Y, Tanimura K, Muro S, Hirai T, Nagai S, Chin K, Mishima M. Matrix
  metalloproteinase-10: a novel biomarker for idiopathic pulmonary fibrosis. Respir
  Res. 2015 Sep 29;16:120. doi: 10.1186/s12931-015-0280-9. PubMed PMID: 26415518;
  PubMed Central PMCID: PMC4587921.
5. Ikezoe K, Handa T, Tanizawa K, Kubo T, Oguma T, Hamada S, Watanabe K, Aihara
  K, Sokai A, Nakatsuka Y, Muro S, Nagai S, Uno K, Chin K, Fukui M, Hirai T,
  Mishima M. Bone mineral density in patients with idiopathic pulmonary fibrosis.
  Respir Med. 2015 Sep;109(9):1181-7. doi: 10.1016/j.rmed.2015.06.014. Epub 2015
  Jul 6. PubMed PMID: 26174191.
6. Oguma T, Hirai T, Fukui M, Tanabe N, Marumo S, Nakamura H, Ito H, Sato S,
  Niimi A, Ito I, Matsumoto H, Muro S, Mishima M. Longitudinal shape irregularity
  of airway lumen assessed by CT in patients with bronchial asthma and COPD.
  Thorax. 2015 Aug;70(8):719-24. doi: 10.1136/thoraxjnl-2014-206651. Epub 2015 May
  29. PubMed PMID: 26024690.
7. Setoh K, Terao C, Muro S, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T,
  Kosugi S, Sekine A, Yamada R, Mishima M, Matsuda F. Three missense variants of
  metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels.
  Nat Commun. 2015 Jul 15;6:7754. doi: 10.1038/ncomms8754. PubMed PMID: 26174136;
  PubMed Central PMCID: PMC4518310.
8. Hasegawa K, Sato S, Tanimura K, Fuseya Y, Uemasu K, Sato A, Hirai T, Mishima
  M, Muro S. Emphysema and airway disease affect within-breath changes in
  respiratory resistance in COPD patients. Respirology. 2015 Jul;20(5):775-81. doi:
  10.1111/resp.12535. Epub 2015 Mar 30. PubMed PMID: 25824559.
2014年
1. Tabara Y, Muro S, Takahashi Y, Setoh K, Kawaguchi T, Terao C, Kosugi S, Sekine
  A, Yamada R, Nakayama T, Mishima M, Matsuda F; Nagahama Study Group. Airflow
  limitation in smokers is associated with arterial stiffness: the Nagahama Study.
  Atherosclerosis. 2014 Jan;232(1):59-64.
2. Marumo S, Hoshino Y, Kiyokawa H, Tanabe N, Sato A, Ogawa E, Muro S, Hirai T,
  Mishima M. p38 mitogen-activated protein kinase determines the susceptibility to
  cigarette smoke-induced emphysema in mice. BMC Pulm Med. 2014 May 7;14:79. doi:
  10.1186/1471-2466-14-79.
3. Kinose D, Ogawa E, Kudo M, Marumo S, Kiyokawa H, Hoshino Y, Hirai T, Chin K,
  Muro S, Mishima M. Association of COPD exacerbation frequency with gene
  expression of pattern recognition receptors in inflammatory cells in induced
  sputum. Clin Respir J. 2014 Jun 5.
4. Tanimura K, Hirai T, Sato S, Hasegawa K, Muro S, Kurosawa H, Mishima M.
  Comparison of two devices for respiratory impedance measurement using a forced
  oscillation technique: basic study using phantom models. J Physiol Sci. 2014
  Sep;64(5):377-82.
5. 室　繁郎
  【COPD治療の新時代　21世紀の「社会的」生活習慣病】 COPDの早期診断,治療の枠組み,急性増悪の対応　新薬乱立の前に知っておくべきこと
  内科(0022-1961)113巻2号 Page217-225(2014.02)
6. 室　繁郎
  【喘息・COPD患者への吸入指導】 COPDの診断と治療　ガイドラインをふまえて
  薬事(0016-5980)56巻3号 Page327-332(2014.03)
7. 佐藤篤靖, 室繁郎
  【COPDを改めて問う】 COPDにおける併存症　気流閉塞、肺気腫いずれに関与しているのか
  THE LUNG-perspectives(0919-5742)22巻2号 Page171-174(2014.05)
8. 室　繁郎
  【COPDの最新情報】 (Topics 5)併存症・合併症のインパクトとその対策
  日本呼吸器学会誌(2186-5876)3巻3号 Page344-351(2014.05)
9. 佐藤晋, 室繁郎
  【疾患と運動時低酸素血症】 COPDと運動時低酸素血症
  呼吸と循環(0452-3458)62巻6号 Page545-551(2014.06)
10. 佐藤晋, 室繁郎, 三嶋理晃
  【高齢者の呼吸器疾患-若年・高齢者発症との違い-】 COPD　若年発症COPDと高齢者COPDについて
  日本胸部臨床(0385-3667)73巻8号 Page876-885(2014.08)
11. 佐藤晋, 室繁郎
  【全身成人病としてのCOPD】 COPDの呼吸機能
  成人病と生活習慣病(1347-0418)44巻9号 Page1013-1018(2014.09)
12. 室　繁郎
  呼吸器疾患診療を支える臨床検査 COPD診療における呼吸機能とCT画像の役割
  臨床病理(0047-1860)62巻12号 Page1212-1217(2014.12)
2013年
1. Tabara Y, Takahashi Y, Setoh K, Muro S, Kawaguchi T, Terao C, Kosugi S, Sekine A, Yamada R, Mishima M, Nakayama T, Matsuda F; on behalf of the Nagahama Study Group. Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: The Nagahama Study. Int J Cardiol. 2013 Apr 8. doi:pii: S0167-5273(13)00447-6. 10.1016/j.ijcard.2013.03.028. [Epub ahead of print]
2. Oguma T, Hirai T, Niimi A, Matsumoto H, Muro S, Shigematsu M, Nishimura T, Kubo Y, Mishima M. Limitations of airway dimension measurement on images obtained using multi-detector row computed tomography. PLoS One. 2013 Oct 8;8(10):e76381. doi: 10.1371/journal.pone.0076381.
3. Tanabe N, Hoshino Y, Marumo S, Kiyokawa H, Sato S, Kinose D, Uno K, Muro S, Hirai T, Yodoi J, Mishima M. Thioredoxin-1 Protects against Neutrophilic Inflammation and Emphysema Progression in a Mouse Model of Chronic Obstructive Pulmonary Disease Exacerbation. PLoS One. 2013 Nov 11;8(11):e79016. doi: 10.1371/journal.pone.0079016.
4. Tabara Y, Muro S, Takahashi Y, Setoh K, Kawaguchi T, Terao C, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda F; Nagahama Study Group. Airflow limitation in smokers is associated with arterial stiffness: The Nagahama Study Atherosclerosis. 2014 Jan;232(1):59-64. doi: 10.1016/j.atherosclerosis.2013.10.020. Epub 2013 Nov 1.
2012年
1. Tanabe N, Muro S, Sato S, Tanaka S, Oguma T, Kiyokawa H, Takahashi T, Kinose
  D, Hoshino Y, Kubo T, Hirai T, Mishima M. Longitudinal study of spatially heterogeneous emphysema progression in current smokers with chronic obstructive
  pulmonary disease. PLoS One. 2012;7(9):e44993. doi: 10.1371/journal.pone.0044993.
  Epub 2012 Sep 18.
2. Suzuki M, Muro S, Ando Y, Omori T, Shiota T, Endo K, Sato S, Aihara K,
  Matsumoto M, Suzuki S, Itotani R, Ishitoko M, Hara Y, Takemura M, Ueda T, Kagioka
  H, Hirabayashi M, Fukui M, Mishima M. A randomized, placebo-controlled trial of
  acupuncture in patients with chronic obstructive pulmonary disease (COPD): the
  COPD-acupuncture trial (CAT). Arch Intern Med. 2012 Jun 11;172(11):878-86.
3. Takahashi T, Muro S, Tanabe N, Terada K, Kiyokawa H, Sato S, Hoshino Y, Ogawa
  E, Uno K, Naruishi K, Takashiba S, Mishima M. Relationship between
  periodontitis-related antibody and frequent exacerbations in chronic obstructive
  pulmonary disease. PLoS One. 2012;7(7):e40570. Epub 2012 Jul 11.
4. Tanabe N, Muro S, Fuseya Y, Sato S, Oguma T, Kiyokawa H, Takahashi T, Kinose
  D, Hoshino Y, Kubo T, Hirai T, Mishima M. Peri-diaphragmatic lung volume assessed
  by computed tomography correlates with quality of life in patients with chronic
  obstructive pulmonary disease. Respirology. 2012 Oct;17(7):1137-43. doi:
  10.1111/j.1440-1843.2012.02221.x.
5. Tanabe N, Muro S, Tanaka S, Sato S, Oguma T, Kiyokawa H, Takahashi T, Kinose
  D, Hoshino Y, Kubo T, Ogawa E, Hirai T, Mishima M. Emphysema distribution and
  annual changes in pulmonary function in male patients with chronic obstructive
  pulmonary disease. Respir Res. 2012 Apr 18;13:31. doi: 10.1186/1465-9921-13-31.
6. Tanabe N, Muro S, Oguma T, Sato S, Kiyokawa H, Takahashi T, Kudo M, Kinose D,
  Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M. Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD. COPD.
  2012 Aug;9(4):401-8. Epub 2012 Apr 18.
7. Kudo M, Ogawa E, Kinose D, Haruna A, Takahashi T, Tanabe N, Marumo S, Hoshino
  Y, Hirai T, Sakai H, Muro S, Date H, Mishima M. Oxidative stress induced
  interleukin-32 mRNA expression in human bronchial epithelial cells. Respir Res.
  2012 Mar 14;13:19.
8. Kiyokawa H, Muro S, Oguma T, Sato S, Tanabe N, Takahashi T, Kudo M, Kinose D,
  Kondoh H, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M. Impact of COPD
  exacerbations on osteoporosis assessed by chest CT scan. COPD. 2012 Jun;9(3):235-42. Epub 2012 Feb 23.
9. Ito Y, Hirai T, Maekawa K, Fujita K, Imai S, Tatsumi S, Handa T, Matsumoto H,
  Muro S, Niimi A, Mishima M. Predictors of 5-year mortality in pulmonary
  Mycobacterium avium-intracellulare complex disease. Int J Tuberc Lung Dis.
  2012;16(3):408-14. Epub 2012 Jan 5.
2011年
1. Matsumoto H, Hirata Y, Otsuka K, Iwata T, Inazumi A, Niimi A, Ito I, Ogawa E,
  Muro S, Sakai H, Chin K, Oku Y, Mishima M. Interleukin-13 enhanced Ca2+
  oscillations in airway smooth muscle cells. Cytokine. 2012 Jan;57(1):19-24. Epub
  2011 Nov 9.
2. Hoshino Y, Muro S, Mishima M. [Novel therapeutics for COPD]. Nihon Rinsho.
  2011 Oct;69(10):1826-30. Review. Japanese.
3. Otsuka K, Matsumoto H, Niimi A, Muro S, Ito I, Takeda T, Terada K, Yamaguchi
  M, Matsuoka H, Jinnai M, Oguma T, Nakaji H, Inoue H, Tajiri T, Iwata T, Chin K,
  Mishima M. Sputum YKL-40 levels and pathophysiology of asthma and chronic
  obstructive pulmonary disease. Respiration. 2012;83(6):507-19. doi:
  10.1159/000330840. Epub 2011 Sep 27.
4. Kinose D, Ogawa E, Hirota T, Ito I, Kudo M, Haruna A, Marumo S, Hoshino Y,
  Muro S, Hirai T, Sakai H, Date H, Tamari M, Mishima M. A NOD2 gene polymorphism
  is associated with the prevalence and severity of chronic obstructive pulmonary
  disease in a Japanese population. Respirology. 2012 Jan;17(1):164-71. doi:
  10.1111/j.1440-1843.2011.02069.x.
5. Tanabe N, Muro S, Hirai T, Oguma T, Terada K, Marumo S, Kinose D, Ogawa E,
  Hoshino Y, Mishima M. Impact of exacerbations on emphysema progression in chronic
  obstructive pulmonary disease. Am J Respir Crit Care Med. 2011 Jun 15;183(12):1653-9. Epub 2011 Mar 11.
2010年
1. Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y,
  Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M.
  Lipopolysaccharide induced connective tissue growth factor gene expression in
  human bronchial epithelial cells. Respirology. 2010 May;15(4):669-76. Epub 2010
  Mar 29.
2. Haruna A, Muro S, Nakano Y, Ohara T, Hoshino Y, Ogawa E, Hirai T, Niimi A,
  Nishimura K, Chin K, Mishima M. CT scan findings of emphysema predict mortality
  in COPD. Chest. 2010 Sep;138(3):635-40. Epub 2010 Apr 9.
3. Haruna A, Oga T, Muro S, Ohara T, Sato S, Marumo S, Kinose D, Terada K,
  Nishioka M, Ogawa E, Hoshino Y, Hirai T, Chin K, Mishima M. Relationship between
  peripheral airway function and patient-reported outcomes in COPD: a cross-sectional study. BMC Pulm Med. 2010 Mar 7;10:10.
2009年
1. IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells.Yamasaki A, Saleh A, Koussih L, Muro S, Halayko AJ, Gounni AS. PLoS One. 2010 Feb 12;5(2):e9178.
2. Sakai H, Nakano Y, Muro S, Hirai T, Takubo Y, Oku Y, Hamakawa H, Takahashi A,
  Sato T, Chen F, Sahara H, Fujinaga T, Sato K, Sonobe M, Shoji T, Miyahara R,
  Okubo K, Bando T, Hirata T, Date H, Mishima M. Age-related changes in the trachea
  in healthy adults. Adv Exp Med Biol. 2010;662:115-20.
3. Terada K, Muro S, Ohara T, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Chin
  K, Mishima M. Abnormal swallowing reflex and COPD exacerbations. Chest. 2010
  Feb;137(2):326-32. Epub 2009 Sep 25.
4. Terada K, Muro S, Ohara T, Haruna A, Marumo S, Kudo M, Ogawa E, Hoshino Y,
  Hirai T, Niimi A, Mishima M. Cough-reflex sensitivity to inhaled capsaicin in
  COPD associated with increased exacerbation frequency. Respirology. 2009
  Nov;14(8):1151-5. Epub 2009 Sep 16.
2008年
1. Ogawa E, Nakano Y, Ohara T, Muro S, Hirai T, Sato S, Sakai H, Tsukino M,
  Kinose D, Nishioka M, Niimi A, Chin K, Paré PD, Mishima M. Body mass index in
  male patients with COPD: correlation with low attenuation areas on CT. Thorax.
  2009 Jan;64(1):20-5. Epub 2008 Oct 13.
2. Sato, A., et al., Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice. J Pharmacol Exp Ther, 2008. 325(2): p. 380-8.
3. Ohara, T., et al., Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography. Respirology, 2008. 13(3): p. 372-8.
4. Terada, K., et al., Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation. Thorax, 2008.
5. Ohara, T., et al., Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD. Chest, 2008.
2007年以前
1. Sato, A., et al., Morphological mechanism of the development of pulmonary emphysema in klotho mice. Proc Natl Acad Sci U S A, 2007. 104(7): p. 2361-5.
2. Ohara, T., et al., Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD. Respirology, 2006. 11(5): p. 579-85.
3. Ito, I., et al., Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema. Am J Respir Crit Care Med, 2005. 172(11): p. 1378-82.
4. Ito, I., et al., Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele. Chest, 2004. 125(1): p. 63-70.
5. Muro, S., et al., 5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin. J Allergy Clin Immunol, 2003. 112(4): p. 768-74.
6. Muro, S., et al., Expression of IL-15 in inflammatory pulmonary diseases. J Allergy Clin Immunol, 2001. 108(6): p. 970-5.
7. Muro, S., E.M. Minshall, and Q.A. Hamid, The pathology of chronic asthma. Clin Chest Med, 2000. 21(2): p. 225-44.
8. Nakano, Y., et al., Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. Am J Respir Crit Care Med, 2000. 162(3 Pt 1): p. 1102-8.
9. Muro, S., et al., Distorted trachea in patients with chronic obstructive pulmonary disease. Respiration, 2000. 67(6): p. 638-44.
10. Nakano, Y., et al., Comparison of low attenuation areas on computed tomographic scans between inner and outer segments of the lung in patients with chronic obstructive pulmonary disease: incidence and contribution to lung function. Thorax, 1999. 54(5): p. 384-9.
11. Mishima, M., et al., Optimized scanning conditions of high resolution CT in the follow-up of pulmonary emphysema. J Comput Assist Tomogr, 1999. 23(3): p. 380-4.
12. Mishima, M., et al., Respiratory impedance during positive expiratory airway pressure in patients with chronic obstructive pulmonary disease. Front Med Biol Eng, 1999. 9(1): p. 63-73.
13. Mishima, M., et al., Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A, 1999. 96(16): p. 8829-34.
14. Takubo, Y., et al., Age-associated changes in elastin and collagen content and the proportion of types I and III collagen in the lungs of mice. Exp Gerontol, 1999. 34(3): p. 353-64.
15. Muro, S., et al., The effect of the level of ventilatory assist on the level of respiratory drive in decerebrate cats. Respir Physiol, 1997. 109(3): p. 205-17.
16. Mishima, M., et al., Relationship between dyspnea in daily life and psycho-physiologic state in patients with chronic obstructive pulmonary disease during long-term domiciliary oxygen therapy. Intern Med, 1996. 35(6): p. 453-8.

呼吸不全・睡眠呼吸障害　｜　間質性肺疾患　｜　COPD　｜　喘息・慢性咳嗽　｜　感染症　｜　肺がん　｜　iPS

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